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studied for dietary fat, breast cancer
04 Oct
2004
Health News, Does less fat equal less breast cancer?
That's a question many Canadian women are asking as
Dr. Norman Boyd's unique diet and breast cancer
study goes into its final year. The oncologist at
the Ontario Cancer Institute had a crazy idea a
decade ago: Why not find thousands of women at risk
of getting breast cancer, deprive them of cookies
and butter and french fries, then see who gets
breast cancer and who doesn't.
The idea that there might be a link between breast
cancer and diet began years ago when studies showed
that women in Japan, eating diets higher in
carbohydrates and lower in fats than women in North
America and Europe, had notably lower rates of the
disease.
"When people migrate from Asia to North America,
their rates change," Boyd said. "So clearly, there
is something in the environment that is affecting
rates. If we can identify that, and change it, then
we can prevent the disease," Boyd says.
Animal experiments have also suggested dietary fat
plays a role, he added. "You can modulate the
frequency with which mammary tumors develop by diet
in small animals."
But would the same apply to humans? To find out,
Boyd and his team are following 4,700 Canadian women
who are at increased risk of breast cancer; they've
studied their eating patterns, compared their
mammograms over the years and gathered tons of data.
The study's participants are between the ages of 30
and 65, were neither pregnant nor breastfeeding, had
no previous cancers and no dietary restrictions.
They were also chosen by density of their breasts:
Breast tissue that shows up dense on a mammogram is
thought to be at increased risk of breast cancer.
Once admitted to the study, the 4,700 were asked to
either change or monitor their eating habits for a
decade. Half were placed on a regular diet. Half
were assigned to follow a diet where the amount of
fat eaten was 15 to 20 per cent of their total
caloric intake. For most of us, that would be
cutting our fat intake by half -- and that's on a
good day when we're not seduced by ice-cream and
chocolate cake.
"We have now followed these good people for several
years," says Boyd, explaining that, as the study
winds down, he and his team will analyse the results
according to the number of breast cancers that have
shown up in each group. He has already shown that a
low-fat diet reduces the density of breasts, but he
hasn't made the link between diet and breast cancer
prevention.
And breast cancers did develop among the women: The
question is, did significantly fewer develop in the
women who were on the low-fat diet? Boyd won't be
giving us any early releases of his results.
While medical science has come a long way in
treating breast cancers and in extending the lives
of many survivors, prevention is still pretty much a
mystery. Aside from the genetic forms of the disease
and the fact that you can prevent a recurrence of
the disease with tamoxifen, a highly toxic drug,
there's very little news on the prevention front,
despite millions of research dollars spent annually.
After all, how can you prevent a disease whose cause
is unknown? Seventy per cent of women with breast
cancer have none of the known risk factors.
So the results of Boyd's study are eagerly awaited.
There is a lot of money riding on prevention, and
many in the research community believe that whatever
it is that causes the disease is sure to be found in
the environment. As women, we want a happy
prevention ending: If broccoli for breakfast every
day would protect us, bring it on in bushels.
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