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MS stem cell trial begins
Reported July 29, 2011
More than 150 patients are set to be involved in a major clinical trial to
investigate whether stem cells can be safely used to treat multiple
sclerosis (MS).
The trial, due to start later this year, has been part-funded by the
UK-based MS Society.
There are hopes that stem cells can be used eventually to slow, stop or even
reverse the damage MS causes to the brain and spinal cord.
Dr Paolo Muraro from Imperial College London said: “There is very strong
pre-clinical evidence that stem cells might be an effective treatment.”
Under the trial, involving patients across Europe, scientists will collect
stem cells from the bone marrow of patients, grow them in the laboratory and
then re-inject them into their blood with the hope they will make their way
to the brain and repair the damage caused by MS.
At present there is no proven stem cell therapy available for MS anywhere in
the world but the MS Society hopes these new trials will eventually lead to
a proven treatment.
Dr Doug Brown, of the MS Society, said: “These experiments have confirmed
that these stem cells hold that potential - but these need to be confirmed
in large scale clinical trials.”
As well as the Imperial College study, the MS Society is also funding two
other stem cell studies; one, based at Queen Mary Hospital, London and the
other, at the University of Nottingham.
Worldwide, some three million people are thought to be affected by MS and up
to 100,000 in the UK.
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