|
Exercise Benefits Leukemia Patients
Reported August 04, 2009
(Ivanhoe Newswire) -- Though it may seem counterintuitive, given that
the most bothersome symptom of leukemia is extreme fatigue, a team of
researchers has shown that physical activity can significantly improve
symptoms of fatigue and depression, increase cardiovascular endurance and
maintain quality of life for adult patients undergoing treatment for
leukemia.
Ten patients undergoing treatment participated in the EQUAL (Exercise and
Quality of Life in Leukemia/ Lymphoma Patients) study at the University of
North Carolina, Chapel Hill, Department of Exercise and Sport Science and
UNC Lineberger Comprehensive Cancer Center. Each patient was provided with
specially-treated exercise equipment to minimize the risk of infection.
Patients participated in individualized exercise sessions while in the
hospital for the 3- to 5-week induction phase of leukemia treatment.
The exercise prescription included aerobic and resistance exercises, core
exercises, and light stretches tailored to the patient's level of fitness
and leukemia symptoms. Upon their discharge from the hospital, each patient
received an aerobic-based exercise prescription for their two-week home
recovery period.
Before and after the exercise program, the researchers measured resting
heart rate, blood pressure and hemoglobin, body weight and height, body
composition, cardiorespiratory fitness and muscular endurance. Researchers
also administered psychological tests to assess fatigue, depression and
quality of life. Blood samples were taken at baseline, mid, and at the
conclusion of the study, and analyzed for biomarkers of inflammation.
"We found that the patients experienced significant reduction in total
fatigue and depression scores, as well as improved cardiorespiratory
endurance and maintenance of muscular endurance," Claudio Battaglini, Ph.D.,
assistant professor of exercise and sport science and UNC Lineberger member
was quoted as saying.
"This is important because of the numerous side-effects related to cancer
treatment, and particularly leukemia treatment, which requires confinement
to a hospital room for 4-6 weeks to avoid the risk of infection,” he added.
“We have demonstrated that these patients not only can complete an exercise
program in the hospital but that they may receive both physiological and
psychological benefits that could assist in their recovery."
A follow-up study, EQUAL phase II, is now in development. This study will
consist of a randomized clinical-controlled trial to assess the effects of
an individualized exercise prescription in acute leukemia patients vs. a
group of leukemia patients receiving treatment with no exercise component.
If the results are positive, the research team will develop a multi-site
research program involving other cancer centers throughout North Carolina
and the United States.
SOURCE: Integrative Cancer Therapies, August 3, 2009 |
