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Eye Cancer: Saving Kids’ Eyes
Reported February 12, 2010
HOUSTON (Ivanhoe Newswire) -- It's a devastating cancer that leads
children into a world of darkness. When kids survive retinoblastoma -- a
cancer that develops in the retina – 97 percent live with a moderate to
severe visual impairment. A new effort is focused on finding treatments that
can save these kids and their eyesight.
Angela Van Beveren saw it in her daughter's eye when she was only a few
weeks old -- a strange glow in her left eye.
"It just seemed like something was not right,” Angela told Ivanhoe.
It was retinoblastoma, tumors inside her daughter Leah's eye. Within a year,
doctors had to remove her eye to stop the cancer.
"At which point, I completely lost it, thinking of my little girl with no
eye,” Angela said.
Today, Leah is a happy six-year-old, with a prosthesis she calls her "hero
eye."
Researchers are working on new treatments to kill the cancer before a
child's eye has to be removed. The first -- suicide gene therapy. Doctors
inject viral particles into the eye then follow it up with a powerful IV
drug. The combination launches an all-out attack on tumor cells.
"The product is poisonous to the cell, and the cell eventually dies because
of that,” Murali Chintagumpala, M.D., a pediatric oncologist at the
Retinoblastoma Center of Houston, told Ivanhoe.
The second new therapy -- proton beam radiation, a more precise treatment
that targets only the tumor.
"We will be able to spare the normal tissues around the eye from the effects
of radiation therapy, thereby reducing long-term side effects including
future cancers,” Dr. Chintagumpala said.
Leah's now celebrating five years cancer-free, a little girl who had to
sacrifice a lot, but is now enjoying every moment of growing up.
For kids whose cancer is stopped in the eye, the cure rate is 95 percent.
It's unclear exactly what causes retinoblastoma, though 30 to 40 percent of
cases are hereditary. In kids with retinoblastoma, it's common for a camera
flash to produce the appearance of a white pupil in photos. The American
Academy of Ophthalmology says if this is the case, take your child to an eye
doctor immediately. |