Cholesterol Guidelines for Kids Need a Second Look
Reported August 07, 2009
(Ivanhoe Newswire) -- With an obesity epidemic brewing among U.S.
children, there is concern that overweight and obese children need to be
screened for chronic medical conditions including high cholesterol levels.
University of Michigan researchers have determined, however, that body fat
is not an effective indicator of high cholesterol in children.
Pediatricians Joyce Lee, M.D., MPH, and Matthew Davis, M.D., MAPP led the
study. "We found, actually, that using body mass index to find kids with
high cholesterol does not work well,” Lee, assistant professor in the
Department of Pediatrics and Communicable Diseases at the U-M Medical School
is quoted as saying. “There were many overweight and obese kids who had
normal cholesterol, and there were a fair number of healthy-weight kids who
had high cholesterol."
The study was conducted in response to the American Academy of Pediatrics (AAP)
revision of its cholesterol screening guidelines in July 2008, advocating a
cholesterol check for kids who have increased risk of heart disease.
Generally, that means all children who are overweight or obese, which is
about 30 percent of kids in the U.S.
"Our results indicate that the AAP guidelines for cholesterol screening in
kids may need to be revised," said Lee. "Otherwise, we may be missing high
cholesterol in some kids and unnecessarily testing others."
The authors performed the study using national data from thousands of
children to see whether 'body mass index' (BMI), a measure of body fat based
on height and weight, is a reliable way to identify children with high
cholesterol levels. They looked at the relationships of BMI to total
cholesterol and to low density lipoprotein (LDL), or “bad,” cholesterol.
Children were classified as overweight if their BMI was between the 85th and
95th percentiles, and defined as obese if their BMI was greater than the
95th percentile for weight based on age and height. Children had abnormal
cholesterol levels if they had total cholesterol greater than 200 mg/dl or
LDL cholesterol level of greater than 130 mg/dl.
This study found that screening all overweight or obese children would
identify approximately 50 percent of children with abnormal cholesterol
levels, but would also lead to unnecessary testing for up to 30 percent of
Other studies have looked at additional screening strategies for abnormal
cholesterol in children on the basis of family history of early heart
disease or high cholesterol. But as Lee notes, "A positive family history
also performs poorly for identifying children with high cholesterol levels.
Therefore, it may be more efficient for the AAP to recommend a public health
campaign to reduce cholesterol among all children, rather than screening
SOURCE: Archives of Pediatric and Adolescent Medicine, August 3, 2009