(Ivanhoe Newswire) -- U.S. researchers may have found a new way to
mend hearts damaged by a heart attack.
They find infusing the patient’s own bone marrow cells into the coronary
artery where the original blockage occurred can lead to long term positive
outcomes.
"These results show that treatment with a patient’s own bone marrow stem
cells has the potential to reduce long-term complications after a heart
attack,” study author Arshed Quyyumi, M.D., was quoted as saying. “We are
encouraged by these results and are planning to conduct a more extensive
study."
The study is similar to others conducted to see if bone marrow cells could
have a positive impact on damaged hearts. But unlike those studies, which
found mixed results, this one used a preparation of cells enriched with
endothelial progenitor cells, which investigators believe play a role in
replenishing the linings of blood vessels.
The addition appears to have made a real difference. Compared to patients
who received no treatment with bone marrow cells following their heart
attacks, those who received the cells had greater improvement in blood flow
during follow up testing. People who received the highest dose experienced
the most benefit.
"This is critical information for future study design -- the more cells a
patient receives, the more beneficial effect we see in the heart," says Dr.
Quyyumi.
SOURCE: Presented at the American College of Cardiology conference March
30, 2009