LOS ANGELES — Nearly two-thirds of those who undergo an invasive heart
test called cardiac catheterization when they do not have diagnosed heart
disease receive a clean bill of health, suggesting that the expensive procedure
— which exposes the patient to substantial amounts of radiation — may be
overused, researchers reported Wednesday.
Such elective testing accounts for only about 20 percent of the 1.5 million
cardiac catheterizations performed in the United States every year, but the
findings reported in the New England Journal of Medicine suggest that better
ways should be found to identify patients who actually need the procedure.
Experts cautioned, however, that the findings should not be viewed with alarm.
Just because a patient does not have a severe obstruction in the arteries "does
not mean that they don't need therapy," said Dr. Gregg C. Fonarow, a
cardiologist at UCLA's Geffen School of Medicine who was not involved in the
research. They may, in fact, need medical treatment or lifestyle alteration.
Fonarow noted that the study concluded that catheterizations had been
unnecessary if artery blockage was 50 percent or less. However, "the majority of
heart attacks occur from lesions that are less than a 50 percent blockage,"
Dr. Steven R. Bailey of the University of Texas Health Science Center at San
Antonio agreed that there is value in detecting disease at its start, before it
becomes a full-fledged problem.
"Knowing that you have the beginnings of the disease can be a very powerful
cause for people to become engaged in their clinical care," said Bailey, who is
president of the Society for Cardiovascular Angiography and Interventions.
And some of the patients who underwent the tests had been restricting activities
such as exercise because of chest pains, he added. "Knowing that they don't have
significant obstructions liberates them to be more active."
The study was conducted by Dr. Manesh Patel, a cardiologist at Duke University
Medical Center, and his colleagues. They studied more than 2 million people who
underwent cardiac catheterization, in which a catheter is inserted through the
groin and threaded through blood vessels to examine the coronary arteries. The
catheterizations had taken place at 663 hospitals that participate in the
American College of Cardiology National Cardiovascular Data Registry, which
tracks such procedures.
Fully 80 percent of the procedures were performed in patients who had previously
diagnosed coronary disease or who were having a heart attack, and no one
questions the value of the test in such cases. The researchers focused on the
398,978 patients who had consistent heart pains but no previous diagnosis of
heart disease. About 84 percent of them had already had a noninvasive test that
suggested the need for further tests.
Patel and his colleagues found that 37.6 percent of the patients had obstructive
coronary artery disease, defined as more than a 50 percent blockage of a
coronary artery. But 39.2 percent of patients had blockages of less than 20
percent while the rest had blockages of between 20 percent and 50 percent.
These data show "that up to two-thirds of the patients undergoing invasive
cardiac catheterization do not have significant obstructive disease," Patel
But that doesn't mean the tests aren't useful, Bailey said. "It's a lot like
having a colonoscopy. You don't find something a lot of the time, but when you
do, it is meaningful and changes the medical care."
Source : STLtoday.com