ORLANDO, Fla. (Ivanhoe Newswire) -- A new vaccine
holds promise in preventing type 1 diabetes -- a disease that strikes 35,000
people each year in the United States.
UCLA Immunologist, Daniel Kaufman, Ph.D., is testing the
vaccine -- called Diamyd --out in mice and is finding if given early enough, it
prevents the animals from developing type 1 diabetes. Human trials have shown it
can help preserve insulin-producing cells in people who have been newly
diagnosed, and the next step will be to see if it can completely prevent the
disease before people are diagnosed, like the vaccine did in mice. But even
keeping the body producing a little bit of insulin is noteworthy because that
helps keep blood glucose levels in check and control some of the long term
complications associated with diabetes.
The vaccine works by slowing down the attack on the immune
system where insulin-producing cells are destroyed.
Kaufman says, "The real goal is to identify the children who
are at high risk for type 1 diabetes and prevent the auto-immune response from
destroying the beta cells... We think that the earlier that we can identify the
children that are destined to develop diabetes and you can change their immune
responses, that they'll be fine for the rest of their lives."
SOURCE: Interview with Daniel Kaufman, Ph.D., of UCLA
Molecular and Medical Pharmacology