Fertility problems in adult women may be linked to heavily drinking in the
teens and early 20s, American researchers said.
A study of two groups of Australian twins found women who were alcoholics
had children later in life but there was no effect among men.
The researchers said women should consider the impact their drinking may
have on their fertility and women who are already having problems conceiving
should not drink at all.
British experts said the results should be viewed with caution because the
study did not distinguish between cause and effect and the findings may be
due to alcoholic women having more relationship problems which delays them
having children.
But Dr Gillian Lockwood Medical Director of Midland Fertility Services,
added that it is biologically plausible that alcohol could affect fertility
because many of the hormones involved in reproduction rely on cholesterol
and that is made in the liver.
She said other research had found that even small amounts of alcohol, just
one or two drinks a week, delayed conception.
Dr Lockwood said: "It is a very real cause for concern, especially as women
are drinking more. We advise women to cut right down on their drinking and
preferably stop."
Steve Hillier, Professor of Reproductive Endocrinology at the University of
Edinburgh, said: "As always, the results of any study involving
retrospective sociodemographic analysis like this need to be treated
cautiously. However, if nothing else they are valuable in alerting us to the
potentially deleterious impact of alcohol abuse on the female reproductive
system."
Mary Waldron, assistant professor of psychiatry at Washington University
School of Medicine, said: "Young women who drink alcohol may want to
consider the longer-term consequences for later childbearing.
"If drinking continues or increases to levels of problem use, their ability
and/or opportunity to have children may be impaired.
Co-author Sharon Wilsnack, professor of clinical neuroscience at the
University of North Dakota School of Medicine & Health Sciences said: "For
women who are already experiencing fertility problems or other reproductive
difficulties the study's findings should warn them not to use alcohol to
cope with stress caused by the reproductive problems, because alcohol would
likely make the reproductive problems worse as well as carrying risks of
possible alcohol abuse or dependence."
The study only looked at women who were dependent on alcohol compared to the
others and did not find a limit where drinking began to have an affect on
fertility.
There is also the possibility that the pain and distress caused by fertility
problems meant those women with impaired fertility were more likely to drink
more, the study published in the journal Alcoholism: Clinical & Experimental
Research said.