A Danish study has found that IVF babies born from
embryos that are frozen are less likely to be underweight or premature than
those conceived during fresh treatment cycles.
Frozen embryos are thawed before they are used and there has been some
concern in the past that the freezing process possibly damages the embryo in
some way.
The researchers found that the average birth weight of those babies was 200g
more than in fresh-embryo IVF and they say the use of frozen embryos could
soon be accepted as a completely safe procedure which can be used even more
frequently.
The team led by Anja Pinborg, of the Copenhagen University Hospital, say the
findings are important because women are increasingly encouraged to use one
fresh embryo in order to avoid multiple births and to freeze any others
produced in the process for use later.
Dr. Pinborg says it is highly unlikely that freezing improved the health of
embryos and a possible explanation might be that the patients who froze
embryos were generally young women with a good prognosis and also that poor
quality embryos were more likely to die during the thawing process.
Dr. Pinborg presented the research at the European Society of Human
Reproduction and Embryology conference in Barcelona this week and says the
findings are reassuring.
Another team of researchers from Yale University also at the conference say
that IVF success rates could be improved by as much as 15 per cent with a
"viability index" for selecting embryos with the best chance of a healthy
pregnancy.
The new "fitness test" can apparently predict which IVF embryos will implant
into the womb up to 70 per cent of the time and is a non-invasive procedure
done from cultures grown in the laboratory.
The team say the technology, known as metabolomics, should be ready for
widespread use within two to three years and could become a routine part of
fertility treatment.