(HealthDay News) -- If you don't get enough vitamin E in
your diet, you may have a greater risk of declining physical function as you
age, according to the findings of a new study.
Yale researchers report that people with the lowest blood levels of vitamin E
have about 60 percent greater odds of a decline in physical function when
compared to people with the highest levels of vitamin E.
"Low plasma levels of vitamin E are associated with subsequent decline in
physical function," said the study's lead author, Benedetta Bartali, a
nutritionist and a Brown-Coxe postdoctoral fellow at Yale University's School of
Medicine.
"As an antioxidant, vitamin E may prevent or reduce the propagation of free
radicals in our body, and this may help to reduce muscle or DNA damage and the
development, for example, of atherosclerosis and other pathologic conditions,"
Bartali said, although she added that this study wasn't designed to identify the
reasons why vitamin E might be helpful.
Results of the study are published in the Jan. 23 issue of the Journal of the
American Medical Association.
In the past, it was believed that vitamin E could help prevent serious illness,
such as heart disease or Alzheimer's. However, more current research found that
excess levels of vitamin E, rather than being helpful, could actually be
harmful. For that reason, it's recommended that people don't take more than 400
I.U.'s [International Units] of vitamin E daily. And the recommended daily dose
is significantly lower than that -- 15 milligrams or 22.5 I.U.'s daily for
anyone over the age of 15, according to the U.S. National Institutes of Health.
Because poor nutrition has been associated with physical decline in older
people, Bartali and her colleagues randomly selected almost 700 adults over age
65 from an ongoing longitudinal study in Tuscany, Italy. They reviewed blood
tests to ascertain vitamin levels and reviewed data from physical function exams
completed at the start of the study and at the three-year follow-up.
After adjusting the data to account for other factors that could contribute to
physical decline, such as smoking or a lack of physical activity, the
researchers found two factors were significantly associated with a greater
chance of experiencing physical decline -- age and low levels of vitamin E.
Levels of B vitamins, vitamin D and iron didn't increase the odds of physical
decline, according to the study.
Being older than 81 years increased the odds of physical decline by 84 percent,
and low levels of vitamin E in people between the ages of 70 and 80 increased
the odds of physical decline by 60 percent, according to the study.
"Because only one person in our study used vitamin E supplements, our results
suggest that an appropriate dietary intake of vitamin E may help to reduce the
decline in physical function among older persons. Whether the use of vitamin E
supplements would yield similar beneficial effects is unknown," Bartali said.
Dr. Kanwardeep Singh, a geriatric specialist at St. John Hospital and Medical
Center in Detroit, said that while this is a very well-done study, it's
difficult to "take the effect of age out of what we are trying to identify."
For now, he said, "I would not recommend vitamin E supplements. My
recommendations would be based on a good nutritious diet, with adequate caloric
intake and adequate exercise. These will take you far beyond vitamin E
supplements" in maintaining physical function.