Pregnant women need them for their babies' brains. Kids need them to learn.
Adults get healthier hearts from them. The do-it-all nutrients known as
omega-3 fatty acids appear to reduce pain in people with rheumatoid
arthritis — and may help treat autism, bipolar disorder, depression,
Alzheimer's disease, ADHD and prostate cancer.
Even dogs and cats need omega-3s to stay healthy.
So eat more fish. Take fish oil pills (or their vegetarian counterparts).
Start buying fortified foods. However you do it, you — like most Americans —
could likely benefit from getting more omega-3 fatty acids, specifically DHA
and EPA.
"There's very strong, medical-nutrition, literature-based evidence in humans
suggesting that the average American would probably have a healthier life, a
lower risk of dying from heart disease and improved brain function by
consuming more fish, more supplements or more functional foods with DHA and
EPA," says nutritional scientist Bruce Holub, of the University of Guelph in
Ontario and executive director of the DHA/EPA Omega-3 Institute there.
But keep in mind, omega-3 fatty acids are not just a single nutrient. The
term refers to a family of compounds that are naturally abundant in fish,
seafood and algae, and it's their surprising chemical variety that may hold
the key to improving our health.
Increasing evidence suggests that each type of omega-3 plays a different
role. The benefits depend on the amount, one's life stage and specific
medical conditions. Such complexity is something that guidelines, at least
in the United States, don't yet reflect.
Researchers are still trying to clarify the details, but some health experts
already are pushing for clearer recommendations that will help people reap
the benefits of omega-3s without wasting money on useless varieties.
"There are strong indications that requirements for many groups should be
higher and that there should be specific requirements for different types of
omega-3s," says Bruce A. Watkins, professor of food science at Purdue
University in West Lafayette, Ind., and director of the International
Omega-3 Learning and Education Consortium for Health and Medicine, an
educational resource.
The various types
Omega-3 fatty acids are long chains of carbon atoms that bond to each other
in different ways to produce molecules with various functions. Out of the
five forms that we consume, the three that matter most to human health are
alpha-linolenic acid (ALA), docosahexaenoic acid (DHA) and eicosapentaenoic
acid (EPA).
Of those three, ALA is the only form that is specified in the United States'
official guidelines with a dietary reference intake. According to the
Institute of Medicine, men should consume 1.6 grams of the fatty acid a day.
Women should get 1.1 grams.
Most Americans easily consume that much. Sources include flax, canola oil,
soybean oil, olive oil, walnuts and other plant-based fats, many of which
people eat every day. There are 1.3 grams of ALA in a tablespoon of canola
oil and 7.6 grams in a tablespoon of flaxseed oil.
The problem is that, on its own, ALA has no known function in the body. The
only reason it's required, Holub says, is because the human body can convert
a small amount of ALA to DHA and EPA, which are far more essential for
healthy brains, hearts and other bodily functions. The amount that gets
converted, however, is not nearly enough.
Accumulating evidence now suggests that it is far more important to consume
DHA and EPA directly — in amounts ranging from 200 milligrams to 4 grams a
day, depending on the person. Salmon, herring, sardines and other oily
varieties of fish have large amounts. Seafood, algae and meat have lesser
amounts.
Although flaxseed doesn't appear to convey the benefits of fish oil, some
algae contain omega-3s that are just as potent as those in fish. Further,
fortified products contain omega-3s derived from the aquatic plants.
The health effects
Interest in fish-based omega-3s spiked in the 1970s, when scientists
observed that Inuit people of Greenland ate tons of fatty fish but had
extremely low rates of heart disease.
Decades later, in a landmark study published in 1999, Italian scientists
studied more than 11,000 men who had suffered heart attacks. After 31/2
years, a group that took about a gram a day of EPA and DHA were 20% less
likely to die than a group that didn't take omega-3 supplements.
In an even larger trial in 2007, Japanese researchers followed more than
18,000 people with high cholesterol for nearly five years and found that
those who took 1.8 grams of EPA a day — in addition to cholesterol-lowering
medications known as statins — were almost 20% less likely to suffer a major
coronary event than people who took statins alone.
Those trials build on hundreds of smaller, more focused studies that clearly
link EPA and DHA with heart health. (EPA and DHA are usually measured, and
taken, together.)
For example, Holub says, studies show that for every extra gram of EPA and
DHA a person takes per day, triglyceride levels drop by 8%, with benefits
showing up in just two weeks. High triglyceride levels are a major risk
factor for heart disease in Americans older than 35. Taking 2 to 4 grams of
EPA and DHA a day for a couple of weeks could reduce levels in the blood by
up to 32% in people with high triglyceride levels.
While EPA and DHA are both essential for heart health — they seem to lower
blood pressure, reduce fat levels in the blood, slow the development of
clots and avert abnormal heart rhythms, among other things — DHA is the star
player in the developing brain and eyes.
Studies show that women who eat at least four servings of fish a week or
take supplements of up to 1.1 grams of DHA daily while pregnant have kids
with higher IQ scores through age 4. Their babies have lower rates of
allergies, better sleep patterns and better vision. DHA-fortified moms also
have lower rates of postpartum depression.
How they work
Scientists have yet to work out many of the details about how omega-3s work
their magic, but inflammation is probably one clue, at least for some
conditions. That would explain why high doses of DHA and EPA on top of more
traditional medicines can reduce morning stiffness and joint pain in
arthritis patients and can help reduce the amount of pain medication people
need to take.
Brain-based disorders are another area of interest. Some studies have found
lower blood levels of omega-3s in adults with Alzheimer's and kids with ADHD
than in comparable groups without those problems.
"All of these pathologies are about things that have to do with cells
misbehaving," says Philip Calder, a nutritionist and omega-3 researcher at
the University of Southampton in England. "You can make cells behave more
optimally by having enough omega-3 fatty acids. Then tissues behave
properly, and you don't have these manifestations of disease."
To some extent, consumers are catching on. In a recent survey of more than
6,000 people who already take supplements, 74% took fish oil or other types
of omega-3 supplements last year, making them more popular than
multivitamins, found ConsumerLab.com, an independent health-products testing
company.
And in 2009, sales of products enriched with omega-3s, omega-6s and omega-9s
jumped by 42% compared with 2008, according to market research firm Nielsen.
Looking ahead
To date, however, most Americans don't appear to be getting nearly enough
omega-3s.
Americans consume fish an average of only once every 10 days, Holub says,
and 50% don't consume fish over a seven-day period. Supplements, meanwhile,
are not a universal dietary staple. As a result, he points out, the average
intake of DHA and EPA in the U.S. is an eighth of what people normally get
in Japan and a quarter of what many experts now think we need.
Food labels aren't especially helpful. The packaging on a box of granola
bars or loaf of bread might tout omega-3s even though they contain a form
that doesn't do much in the body or their concentrations of nutrients might
be too small to make a difference.
And even when detailed information is available, it's not always clear how
much a given individual should get.
Regardless, consumption needs to rise, nutrition experts say.
"Why have societies consumed fish for so many centuries?" Watkins says. "I
think we're just beginning to understand the benefits."
Source : The Los Angeles Times