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Oxytocin: 'Love Hormone' Demystified


 Oxytocin: 'Love Hormone' Demystified

Women Fitness has made a sincere attempt to demystify oxytocin the 'Love Hormone' . Oxytocin is also called "love hormone" is being increasingly shown to trigger a wide variety of physical and psychological effects in both women and men. The hormone's influence on our behavior and physiology originates in the brain, where it's produced by the by a structure called the hypothalamus, and then transfers to the pituitary gland which releases into the bloodstream.. Like antennas picking up a signal, oxytocin receptors are found on cells throughout the body. Levels of the hormone tend to be higher during both stressful and socially bonding experiences, according to the American Psychological Association.

"It's like a hormone of attachment, you might say," said Carol Rinkleib Ellison, a clinical psychologist in private practice in Loomis, California and former assistant clinical psychiatry professor at the University of California, San Francisco. "It creates feelings of calm and closeness."

Thought scientists have long known about oxytocin's rolein breastfeeding and childbirth, "We're just learning more about it now," Ellison said. Widely dubbed the love hormone, numerous other names have been given to oxytocin recently - hug hormone, cuddle chemical, moral molecule, bliss hormone - since researchers have begun to uncover its effects on behavior, including its role in love, in addition to its female biological functions in reproduction.

Oxytocin is a mammalian neurohypophysial hormone. Produced in the supraoptic and paraventricular nuclei of the hypothalamus by nerve axons, and stored in the posterior pituitary gland, oxytocin acts primarily as a neuromodulator in the brain.

Oxytocin plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction of both sexes, in particular during and after childbirth. It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, and, after stimulation of the nipples, lactation. Both childbirth and milk ejection result from positive feedback mechanisms.
 

Recent studies have begun to investigate oxytocin's role in various behaviors, including orgasm, social recognition, pair bonding, anxiety, and maternal behaviors. For this reason, it is sometimes referred to as the "bonding hormone". There is some evidence that oxytocin promotes ethnocentric behavior, incorporating the trust and empathy of in-groups with their suspicion and rejection of outsiders. Furthermore, genetic differences in the oxytocin receptor gene (OXTR) have been associated with maladaptive social traits such as aggressive behaviour.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.

Oxytocin is a hormone that is made in the brain, in the hypothalamus, and it is transported to, and secreted by, the pituitary gland, which is located at the base of the brain.

Chemically it is known as a nonapeptide (a peptide containing nine amino acids), and biologically, as a neuropeptide. It acts both as a hormone and as a brain neurotransmitter.

The release of oxytocin by the pituitary gland acts to regulate two female reproductive functions:

  • Childbirth

  • Breast-feeding.

 Oxytocin: 'Love Hormone' DemystifiedThe release of the hormone during labor makes the muscles of the uterus, womb, contract - in other words, it increases uterine motility. The release of oxytocin is triggered by the widening of the cervix and vagina during labor, and this effect is in turn increased by the subsequent contractions. The main role of oxytocin is summed up nicely in a research paper by obstetric and gynecology specialists Navneet Magon and Sanjay Kalra:

"It is released in large amounts during labor, and after stimulation of the nipples. It is a facilitator for childbirth and breastfeeding."

Other researchers sum up the reproductive importance of oxytocin by saying it "serves the continued propagation of a species," adding that through evolution its "repertoire has expanded to maintain a central role in more complicated aspects of reproductive behavior. For these reasons, we call oxytocin the great facilitator of life."

Oxytocin, used as a prescription drug, is also known by the brand name Pitocin.

Doctors prescribe oxytocin to start birth contractions or strengthen them during labor. It is also used to reduce bleeding after child delivery. The drug also has a role in the medical termination of pregnancy or during miscarriage.

 

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Dated 12 May 2015

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