(Ivanhoe Newswire) -- Breast cancer occurs more frequently in certain
ethnic and racial groups, but the reasons behind these differences are not fully
understood. For example, factors known to increase the risk of breast cancer
among white women have less influence in Hispanic women.
Lisa Hines, ScD, of the University of Colorado at Colorado Springs, and
colleagues conducted a study that considered how established breast cancer risk
factors—including reproductive history, family history of breast cancer,
menstrual history, hormone use, alcohol consumption, physical activity, height,
and body mass index—might be involved in explaining some of the observed
differences in the occurrence of breast cancer among racial and ethnic groups.
They studied breast cancer among women from the Southwest United States who were
enrolled in the population-based, case-control 4-Corners Breast Cancer Study,
which investigated factors that contribute to the difference in breast cancer
incidence rates observed between Hispanic and non-Hispanic white women.
In
this study, the researchers found that 62 to 75 percent of breast cancer cases
among non-Hispanic white women were attributed to known breast cancer risk
factors, compared with only 7 to 36 percent of cases among Hispanic women.
Hispanic women were more likely to have characteristics associated with lower
breast cancer risk, such as earlier age at first childbirth, having more
children, shorter height, less hormone use, and less alcohol consumption.
Among premenopausal women, taller height and family history of breast cancer
were associated with increased risk in non-Hispanic white women, but not among
Hispanic women. Among postmenopausal women, certain breast cancer risk factors
in non-Hispanic whites, such as recent hormone therapy use and younger age at
menarche, had little or no associations with breast cancer in Hispanics.
These findings suggest that many of the risk factors studied to date explain
fewer of the breast cancer cases that arise in Hispanic women. "These
differences are likely to contribute to disparities in breast cancer incidence
rates, and could potentially reflect differences in breast cancer development
among these ethnic groups," Dr. Hines was quoted as saying. For example, ethnic
differences in genetic and environmental or lifestyle factors may affect
individuals' susceptibility to the development of breast cancer.
SOURCE: Cancer, online, April 26, 2010