Both time-restricted eating (TRE) and high-intensity interval training (HIIT) have been shown to improve cardiometabolic health in people who are overweight and at risk of serious disease. Now a randomized, controlled trial has tested whether combining these two approaches is more effective than either of them on their own. The results, publishing in the journal Cell Metabolism … [Read more...]
Women Health News
Scientists Chart How Exercise Affects The Body
Exercise is well-known to help people lose weight and avoid gaining it. However, identifying the cellular mechanisms that underlie this process has proven difficult because so many cells and tissues are involved. In a new study in mice that expands researchers' understanding of how exercise and diet affect the body, MIT and Harvard Medical School researchers have mapped out … [Read more...]
Promising Treatment For Dementia
Behavioural variant frontotemporal dementia (bvFTD) is a rapidly progressing destructive disease and can occur in people as young as 35 years of age. It is characterised by behavioural disturbances and personality changes and can be highly disruptive and distressing for both patients and their families. Currently there are no treatments or cures for bvFTD and typical survival … [Read more...]
How Migraine Pain Signals are Generated, and Blocked
An international team of researchers has discovered that Schwann cells -- which are abundant in the peripheral nervous system and create a protective sheath around nerve fibers -- play an essential role in migraine pain. Their study, conducted in mice and human Schwann cells and published in Nature Communications, illustrates how pain is signaled from within Schwann cells and … [Read more...]
Overlooked Disease: Tens of Thousands of People have Problems at work
Imagine your head pounding. And when you try to move, a door slams, or curtains are drawn it gets much worse. Ideally, you would like to crawl under your blanket in a dark and quiet room. This is how it may feel for people suffering from migraine or frequent tension headaches. Untreated, a migraine attack may last for 4-72 hours, and tension headaches may potentially last … [Read more...]
Highly Responsive Immune Cells Seem to be Beneficial For The Brain
Findings by researchers from Germany support the view that hyperactive immune cells in the brain can have a protective effect in the course of neurodegenerative diseases. Experts from Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Ludwig-Maximilians-Universität München (LMU) and LMU Klinikum München report on this in the scientific magazine The EMBO Journal. The … [Read more...]
New Method for Stimulating Signaling to Improve Metabolic Health and Possibly Treat Obesity
Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors … [Read more...]
Overactive Bladder and Urinary Incontinence Worsen with Age
If you're feeling more sudden urges to run to the bathroom as you age, you're not alone. A new study suggests postmenopausal women aged 45 to 54 years are more likely to have overactive bladder (OAB) syndrome. Additionally, obesity and multiple births put a woman at greater risk for stress urinary incontinence (SUI). Study results are published online today in Menopause, the … [Read more...]
‘Broken heart’ syndrome is on the rise in women
The study, published in the Journal of the American Heart Association (JAHA), suggests middle-aged and older women are being diagnosed with broken heart syndrome more frequently -- up to 10 times more often -- than younger women or men of any age. The research also suggests that the rare condition has become more common, and the incidence has been rising steadily since well … [Read more...]
Higher fasting ‘hunger hormone’ levels from healthy diet may improve heart health and metabolism
Fasting levels of the "hunger hormone" ghrelin rebound after weight loss and can help reduce belly fat and improve the body's sensitivity to insulin, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. Ghrelin is a stomach-derived hormone that stimulates appetite. Ghrelin levels rise during overnight fasting when a … [Read more...]
Antibiotic Levels Measurable in Breath
A team of engineers and biotechnologists at the University of Freiburg has for the first time shown in mammals that the concentration of antibiotics in the body can be determined using breath samples. The breath measurements also corresponded to the antibiotic concentrations in the blood. The team's biosensor -- a multiplex chip that allows simultaneous measurement of several … [Read more...]
MIND Diet Linked to Better Cognitive Performance
Aging takes a toll on the body and on the mind. For example, the tissue of aging human brains sometimes develops abnormal clumps of proteins that are the hallmark of Alzheimer's disease. How can you protect your brain from these effects? Researchers at Rush University Medical Center have found that older adults may benefit from a specific diet called the MIND diet even when … [Read more...]
Many COVID-19 Patients Produce Immune Responses Against their Body’s Tissues or Organs
A University of Birmingham-led study funded by the UK Coronavirus Immunology Consortium has found that many patients with COVID-19 produce immune responses against their body's own tissues or organs. COVID-19 has been associated with a variety of unexpected symptoms, both at the time of infection and for many months afterwards. It is not fully understand what causes these … [Read more...]
Researchers Develop New Measure of Brain Health
How old is your brain compared to your chronological age? A new measure of brain health developed by researchers at Rush University Medical Center may offer a novel approach to identifying individuals at risk of memory and thinking problems, according to research results published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association on June 1. Dubbed … [Read more...]
Brain Changes Following Traumatic Brain Injury Share Similarities With Alzheimer’s Disease
Brain changes in people with Alzheimer's disease and in those with mild traumatic brain injuries (TBIs) have significant similarities, a new USC study shows, suggesting new ways to identify patients at high risk for Alzheimer's. The findings appear this week in GeroScience. TBIs, which affect over 1.7 million Americans every year, are often followed by changes in brain … [Read more...]
Non-invasive Skin Swab Samples can Quickly Detect COVID-19, a New Study Finds
Researchers at the University of Surrey have found that non-invasive skin swab samples may be enough to detect COVID-19. The most widely used approach to testing for COVID-19 requires a polymerase chain reaction (PCR) test, which involves taking a swab of the back of the throat and far inside the nose. In a paper published by Lancet E Clinical Medicine, chemists from Surrey … [Read more...]
Prolonged Immune Response may Contribute to Post-COVID-19 Blood Clots
Serious complications due to blood clots, such as heart attacks and strokes, that are experienced by some COVID-19 survivors may be caused by a lingering immune response in the blood vessels after recovery, suggests a study published today in eLife. The findings may help explain why some COVID-19 survivors, so-called 'long-haulers', report lasting COVID-19 symptoms or why some … [Read more...]
Sleep Helps keep teens good mental health
As families settle back into a new school year, sleep experts at the University of South Australia are reminding parents about the importance of teenagers getting enough sleep, cautioning them that insufficient sleep can negatively affect their mental health. In a new research paper, UniSA sleep experts Dr Alex Agostini and Dr Stephanie Centofanti confirm that sleep is … [Read more...]
Warning Signs over Effectiveness of HIV ‘wonder drug’ in Sub-Saharan Africa
Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa, suggests new research published on World AIDS Day. The study finds that this so-called 'wonder drug' may be less effective in patients resistant to older drugs. As HIV copies itself and replicates, it can develop errors, or 'mutations', in its genetic code (its … [Read more...]
A sulfur molecule to block the coronavirus
The cell membrane is impermeable to viruses: to get inside and infect a cell, they use a range of strategies to exploit the cellular and biochemical properties of the membranes. The thiol-mediated uptake of organic molecules similar to alcohols, where oxygen is replaced by a sulfur atom, is one of the entry mechanisms, with its use by Human Immunodeficiency Virus (HIV) … [Read more...]
Estrogen may Lessen Severity of COVID-19 Symptoms in Women, study finds
Why are men at greater risk than women for more severe symptoms and worse outcomes from COVID-19 regardless of age? In an effort to understand why this occurs, scientists at Wake Forest School of Medicine conducted a review of published preclinical data on sex-specific hormone activity, especially estrogen. The review is published in the September online issue of the … [Read more...]
PROSIT app tracks your mental health based on how you use your phone
Have you ever wondered if your phone is helpful or harmful to your mental health? Well, now there's an app that could tell you. As our phones get smarter by the year, the debate around just how detrimental they might be to our mental health continues without any definitive resolution. Does using Instagram make you aspirational or just plain … [Read more...]
UK’s vaccine against SARS-CoV-2 is safe and induces an immune reaction, according to preliminary results
Promising early stage results from a phase 1/2 clinical trial of the UK's vaccine candidate against SARS-CoV-2 (the virus that causes COVID-19) are published today in The Lancet. The early stage trial finds that the vaccine is safe, causes few side effects, and induces strong immune responses in both parts of the immune system -- provoking a T cell response within 14 days of … [Read more...]
Study confirms ‘classic’ symptoms of COVID-19
A persistent cough and fever have been confirmed as the most prevalent symptoms associated with COVID-19, according to a major review of the scientific literature. Other major symptoms include fatigue, losing the ability to smell and difficulty in breathing. The study ratifies the list of symptoms listed by the World Health Organisation at the start of the … [Read more...]
Physical activity in all of its forms may help maintain muscle mass in midlife
A large study of middle-aged women shows that age-related changes in skeletal muscle are part of everyday life for women in their fifties. During this time, women transition from perimenopause to postmenopause and the production of estrogen ceases. Loss of estrogen has an effect on muscles and leads to a decline in muscle mass. Physical activity in all of its forms may help … [Read more...]
Repetitive negative thinking linked to dementia risk
Persistently engaging in negative thinking patterns may raise the risk of Alzheimer's disease, finds a new UCL-led study. In the study of people aged over 55, published in Alzheimer's & Dementia, researchers found 'repetitive negative thinking' (RNT) is linked to subsequent cognitive decline as well as the deposition of harmful brain proteins linked to … [Read more...]
Vitamin B3 revitalizes energy metabolism in muscle disease
An international team of scientists, led by University of Helsinki reported that vitamin B3, niacin, has therapeutic effect in progressive muscle disease. Niacin delayed disease progression in patients with mitochondrial myopathy, a progressive disease with no previous curative treatments. Vitamin B3 forms have recently emerged as potent boosters of energy metabolism in … [Read more...]
A disease trigger for pancreatitis has been identified
Patients suffering from chronic pancreatitis experience an either recurring or permanent inflammation of their pancreas. "In many cases, people develop this disease because they are drinking too much alcohol or they are smoking too much. Certain medication or high levels of lipids or calcium in a patient's blood can be another cause of pancreatitis," explained Heiko Witt, one … [Read more...]
Aerobics may be a smart workout for your brain at any age
It's never too late to lace up some sneakers and work up a sweat for brain health, according to a study published in the May 13, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study suggests older adults, even couch potatoes, may perform better on certain thinking and memory tests after just six months of aerobic … [Read more...]
Coffee linked to lower body fat in women
Women who drink two or three cups of coffee a day have been found to have lower total body and abdominal fat than those who drink less, according to a new study published in The Journal of Nutrition. Researchers examined data from the National Health and Nutrition Examination Survey, organised by the Center for Disease Control (CDC) in the United States and looked at the … [Read more...]
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