Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT Southwestern reports in a new study. The findings, published online in PNAS, could offer a new way to treat both Type 1 and Type 2 diabetes in people. More than 34 million Americans have … [Read more...]
Diabetes News

Dental experts discover biological imbalance is the link between gum and kidney disease
An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study led by the University of Birmingham has found. Periodontitis -- or gum disease -- is a common, inflammatory disease which causes bleeding gums, wobbly or drifting teeth and can eventually result in … [Read more...]
Routine eye scans may give clues to cognitive decline in diabetes
As they age, people with diabetes are more likely to develop Alzheimer's disease and other cognitive disorders. Scientists at Joslin Diabetes Center now have shown that routine eye imaging can identify changes in the retina that may be associated with cognitive disorders in older people with type 1 diabetes. These results may open up a relatively easy method for early … [Read more...]
Researchers Urge Priority Vaccination for Individuals with Diabetes
Vanderbilt University Medical Center researchers have discovered individuals with type 1 and type 2 diabetes infected with COVID-19 are three times more likely to have a severe illness or require hospitalization compared with people without diabetes. Because of this amplified impact, they are urging policymakers to prioritize these individuals for COVID-19 vaccination. … [Read more...]
Study Connects Diabetes, Air Pollution to Interstitial Lung Disease
People with pre-diabetes or diabetes who live in ozone-polluted areas may have an increased risk for an irreversible disease with a high mortality rate. A new study published in the Environmental Health Perspectives connects insulin resistance and repetitive ozone exposure to the development of interstitial lung disease. "Our findings are especially important today as … [Read more...]
Molecular Processes in Kidney Cells discovered that attract and feed COVID-19
Although the lungs are a common target for COVID-19's cytokine storm, so are the kidneys, making the 1 in 4 U.S. adults with diabetes resulting in diabetic kidney disease at increased risk for virus mortality. Why are the kidneys so attractive to the coronavirus? Recently published in Kidney International, a national research team made up of kidney clinicians, … [Read more...]
How changing the stem cell response to inflammation may reverse periodontal disease
Periodontal disease, also known as gum disease, is a serious infection that affects nearly 50 percent of Americans aged 30 years and older. If left unchecked, periodontal disease can destroy the jawbone and lead to tooth loss. The disease is also associated with higher risk of diabetes and cardiovascular disease. The current treatment for periodontal disease involves … [Read more...]
Urine Test Reveals Quality of Your Diet — and Whether it’s the Best Fit for Your Body
Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'. Scientists at Imperial College London in collaboration with colleagues at Northwestern University, University of Illinois, and Murdoch University, analysed levels of 46 different so-called … [Read more...]
Obesity is a critical risk factor for type 2 diabetes, regardless of genetics
Obesity increases the risk of developing type 2 diabetes by at least 6 times, regardless of genetic predisposition to the disease, concludes research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]). The study is by Dr Theresia Schnurr and Hermina Jakupovi?, Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty … [Read more...]
A non-invasive way of monitoring diabetes
Saliva could be used instead of blood to monitor diabetes in a method proposed in research involving the University of Strathclyde. The test has been developed as an alternative to the current prevalent practice of monitoring blood glucose, which can be invasive, painful and costly. Lab tests of the saliva process had an accuracy rate of 95.2%. The research shows … [Read more...]
How enzymes build ‘sugar trees’
Many of the membrane proteins in eukaryotic cells are decorated with complex sugar trees called glycans. In addition to being extremely diverse, these sugar trees serve as a way to identify the respective organism, a cell type or its stage of maturity. For instance, the various blood groups in humans feature different glycans. Complex sugars that are attached to … [Read more...]
Avocados may help manage obesity, prevent diabetes
Your guacamole may hold the key to managing obesity and helping delay or prevent diabetes, according to a new study by a University of Guelph research team. For the first time, researchers led by Prof. Paul Spagnuolo have shown how a compound found only in avocados can inhibit cellular processes that normally lead to diabetes. In safety testing in humans, the team also … [Read more...]
Type 2 diabetes remission possible with ‘achievable’ weight loss
The findings suggest that it is possible to recover from the disease without intensive lifestyle interventions or extreme calorie restrictions. Type 2 diabetes affects 400 million people worldwide and increases the risk of heart disease, stroke, blindness and amputations. While the disease can be managed through a combination of positive lifestyle changes and medication, it … [Read more...]
Fatty fish without environmental pollutants protect against type 2 diabetes
Research on the effect of fish consumption on diabetes risk has produced contradictory results in recent years. Some studies show that eating a lot of fish reduces the risk of developing type 2 diabetes, while others show it has no effect, and some studies show it even tends to increase the risk. Researchers at Chalmers University of Technology conducted a study with an … [Read more...]
Breastfeeding reduces child obesity risk by up to 25%, WHO
Breastfeeding can cut the chances of a child becoming obese by up to 25%, according to a major study involving 16 countries. World Health Organisation (WHO) experts who led the Europe-wide research are calling for more help and encouragement to women to breastfeed, as well as curbs on the marketing of formula milk which, said senior author Dr João Breda, misled women into … [Read more...]
Drug reduces risk of kidney failure in people with diabetes
A new landmark clinical trial shows that a drug lowers the risk of kidney failure by a third in people with Type 2 diabetes and kidney disease. "For the first time in 18 years, we have a therapy for patients with Type 2 diabetes and chronic kidney disease that decreases kidney failure," said Kenneth Mahaffey, MD, professor of medicine at the Stanford University School of … [Read more...]
Alcohol intake may be key to long-term weight loss for people with Diabetes
Research shows that losing weight can help prevent or delay the onset of diabetes. While best practice for weight loss often includes decreasing or eliminating calories from alcohol, few studies examine whether people who undergo weight loss treatment report changes in alcohol intake and whether alcohol influences their weight loss. A new study from the University of … [Read more...]
Blood Test in Early Pregnancy May Predict Mom’s Diabetes Risk
A blood test seems to detect signs of gestational diabetes as early as the 10th week of pregnancy, a new U.S. government study says. Gestational diabetes occurs only in pregnancy and can pose a serious health threat to mothers and babies. It increases the mother's risk of pregnancy-related high blood pressure disorders, cesarean delivery, as well as heart disease and … [Read more...]
Diabetes during pregnancy may increase baby’s heart disease risk
Gestational diabetes may increase the risk of blood vessel dysfunction and heart disease in offspring by altering a smooth muscle protein responsible for blood vessel network formation. Understanding of the protein's function in fetal cells may improve early detection of disease in children. Gestational diabetes, a state of prolonged high blood sugar during pregnancy, … [Read more...]
Clinical trial examines impact of high-dose omega-3 and vitamin D on halting type 1 diabetes
Scientists from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine today announced the launch of a new clinical trial that will assess the impact of high-dose omega-3 fatty acids and vitamin D supplementation on halting the progression of type 1 diabetes (T1D). The DRI has received FDA IND clearance to proceed with the Phase I/IIa trial, … [Read more...]
Lentils significantly reduce blood glucose levels
Replacing potatoes or rice with pulses can lower your blood glucose levels by more than 20 per cent, according to a first-ever University of Guelph study. Prof. Alison Duncan, Department of Human Health and Nutritional Sciences, and Dan Ramdath of Agriculture and Agri-Food Canada, found that swapping out half of a portion of these starchy side dishes for lentils can … [Read more...]
Abnormal lipid metabolism in fat cells predicts future weight gain and diabetes in women
The inefficient breakdown of fats predicts later weight gain and metabolic complications such as type 2 diabetes in women, researchers report in the journal Cell Metabolism. Low levels of hormone-stimulated lipolysis -- a biochemical process by which triglycerides are broken down into energy-rich fatty acids -- were associated with weight gain and metabolic problems 13 years … [Read more...]
Why zero-calorie sweeteners can still lead to diabetes, obesity
Increased awareness of the health consequences of eating too much sugar has fueled a dramatic uptick in the consumption of zero-calorie artificial sweeteners in recent decades. However, new research finds sugar replacements can also cause health changes that are linked with diabetes and obesity, suggesting that switching from regular to diet soda may be a case of 'out of the … [Read more...]
Unexpected finding may deter disabling diabetic eye disease
A new Michigan State University study is the first to find that a particular type of lipid, or fat, thought to only exist in the skin, now lives in your eye and might play a major role in deterring the eye disease. "Our study presents an unexpected finding that the connections between cells in the retinal blood vessels contain unusual, long-chain lipids that may keep vessels … [Read more...]
Bloodless revolution in diabetes monitoring
The patch does not pierce the skin, instead it draws glucose out from fluid between cells across hair follicles, which are individually accessed via an array of miniature sensors using a small electric current. The glucose collects in tiny reservoirs and is measured. Readings can be taken every 10 to 15 minutes over several hours. Crucially, because of the design of the … [Read more...]
Fiber-fermenting bacteria improve health of type 2 diabetes patients
The fight against type 2 diabetes may soon improve thanks to a pioneering high-fiber diet study led by a Rutgers University-New Brunswick professor. Promotion of a select group of gut bacteria by a diet high in diverse fibers led to better blood glucose control, greater weight loss and better lipid levels in people with type 2 diabetes, according to research published … [Read more...]
Arsenic-tainted drinking water may increase diabetes risk
A new study reports that chronic exposure to arsenic interferes with insulin secretion in the pancreas, which may increase the risk of diabetes. The paper, published ahead of print in the American Journal of Physiology -- Regulatory, Integrative and Comparative Physiology, was chosen as an APSselect article for January. Arsenic is an element that occurs … [Read more...]
Hot flashes could be precursor to diabetes, study suggests
Hot flashes, undoubtedly the most common symptom of menopause, are not just uncomfortable and inconvenient, but numerous studies demonstrate they may increase the risk of serious health problems, including heart disease. A new study suggests that hot flashes (especially when accompanied by night sweats) also may increase the risk of developing diabetes. Results are being … [Read more...]
Mature B lymphocytes accelerate the healing of diabetic ulcers, other skin injuries
A Massachusetts General Hospital (MGH) research team has found a surprising potential solution to a persistent clinical problem -- the healing of chronic wounds. In their report published in Wound Repair and Regeneration, the investigators from the MGH Vaccine and Immunotherapy Center (VIC) describe how application of mature B lymphocytes -- the immune cells best known for … [Read more...]
Understanding how gastric bypass works: Finding drug targets for obesity and diabetes
A study by a team of researchers at the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) and Shriners Hospital for Children has made a technological advancement toward accelerating the discovery of drug targets for obesity, type II diabetes and other metabolic diseases. The novel experimental and computational workflow involves the first use of rodent … [Read more...]
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