ORLANDO, Fla. (Ivanhoe Newswire) -- It's likely in your fridge and now,
scientists are studying it to help patients with type one diabetes. Lettuce
could soon help the millions of people in the United States diagnosed with this
chronic disease.
Mike Beckman has been living with type 1 diabetes for 34 years -- something he
just can't forget about.
"It's with you every day," he told Ivanhoe. "Every day it is with you."
He's had bleeding in his eyes, a heart attack, nerve damage and now, both of his
kidneys are failing. The disease has taken its toll on his body … and his family
life.
"I have a very young daughter," Beck said. "I'd like to see her grow up and see
grandchildren."
Soon researcher Henry Daniell may have an answer for people like mike … and it
could come from lettuce.
"This is a totally new concept," Henry Daniell, Ph.D., a molecular biologist at
the University of Central Florida in Orlando, Fla., told Ivanhoe.
For the past 20 years, Dr. Daniell has worked to perfect the method. He injects
the human gene for insulin into leaves of lettuce that are grown in the lab. The
leaves can be ground into a powder and put into a capsule.
"What we have done is teach the body how to cure this disorder," Dr. Daniell
said.
The lettuce helps the powdered capsule reach the intestine. There, plant cells
meet with bacteria and release the insulin. This stimulates an immune response
and tells the body to produce its own insulin.
The first test was in animals. After eight weeks, all the diabetic mice had
normal blood sugar levels and produced insulin -- even after they stopped taking
the lettuce. Now, human trials are planned. Dr. Daniell says if all goes well,
this could be a permanent solution.
"It would mean everything in the world to me. I could literally give up
everything, other than my family, to have a cure," Beckman proclaimed. Research
is one step closer to giving him just that.
Dr. Daniell says patients would only have to take the pill for weeks, not months
or years. Once their immune system responds, they would essentially no longer
have the disease. He also says because this is a plant-based therapy, it would
only cost pennies to produce. There were no side effects observed in the mice.
Human trials are expected to start in the next year.
FOR MORE INFORMATION, PLEASE CONTACT:
Henry Daniell, PhD
University of Central Florida, College of Medicine
daniell@mail.ucf.edu
http://daniell.ucf.edu