(Ivanhoe Newswire) – Good blood could run in your
blood! New research shows high levels of HDL cholesterol
(HDL-C), also known as “good” cholesterol, could arise
from a genetic mutation.
Researchers found mutations in the LIPG gene, which
codes for the endothelial lipase enzyme, result in high
plasma HDL-C levels. Individuals with high plasma HDL-C
levels are at a decreased risk of developing coronary
artery disease – a condition where plaque builds up
inside the coronary arteries, putting the patient at an
increased risk of heart attack.
Based on this data, researchers report inhibition of
endothelial lipase is likely to raise HDL-C levels in
humans. However, further research will need to be
conducted to determine if the rise in HDL-C levels could
impact cardiovascular health.
SOURCE: The Journal of Clinical Investigation, 2009
