(HealthDayNews) -- A drink a day may keep dementia away. That's the conclusion of a new study that found that older women who had one
alcoholic drink a day had a 20 percent reduced risk of cognitive impairment,
compared to women who abstained. This small benefit may translate into bigger benefits later in life.
"A decent proportion of women we see who are having more memory changes than
other women will go on to get dementia," said senior study author Francine
Grodstein, an associate professor of medicine at Brigham and Women's Hospital
and Harvard Medical School.
"If alcohol at moderate levels is helping to prevent some changes in memory
today, that most likely will translate 10 years from now into them being less
likely to develop dementia," she added.
The findings appear in the Jan. 20 issue of the New England Journal of
Medicine.
Dr. Denis A. Evans, author of an accompanying editorial in the journal, noted
that Grodstein's work was an observational study, and so deserves caution.
"This is a step down the road, rather than something that leads to absolutely
definite conclusions," said Evans, director of the Rush Institute for Healthy
Aging in Chicago. "But that doesn't detract from its [the study's] importance in
this context."
While experts know that excessive alcohol intake on a regular basis can
damage the brain, it has been unclear what the effects of moderate consumption
might be. Light drinking has been linked to several positive health results,
including a decreased risk of cardiovascular
disease. Given that cardiovascular disease and cognitive impairment share risk
factors, it makes sense that light drinking might also benefit memory and other
aspects of cognitive functioning, Grodstein said.
"There's increasing evidence that the same things that are good or bad for
the heart are also good or bad for the brain," she explained.
Grodstein and her colleagues collected information on alcohol consumption
from 12,480 women, aged 70 to 81, who participated in the Nurse's Health Study.
Moderate consumption was defined as less than 15 grams (one glass) per day of
beer, wine or liquor. The study authors then assessed the participants'
cognitive functioning.
Women who drank one-half to one glass of alcohol per day had better cognitive
scores than teetotalers. Such moderate consumption appeared to produce a 20
percent reduced risk of cognitive impairment. There seemed to be no difference
between those who had more than one drink per day and those who abstained. And
there didn't appear to be any difference in the effects of different alcohol
beverages.
Because the study was an observational one, there are certain caveats. For
one thing, the editorial pointed out, people who consume small amounts of
alcohol seem to have better health than people who don't drink at all. It's
therefore possible that the changes in cognition could be attributable to
something other than alcohol intake.
"In general, people who are older who indulge in very light alcohol
consumption, less than one drink per day, are probably a little bit healthier
than those who don't, on average," Evans said.
There is also the issue of how often the researchers measured cognition --
just twice during the seven-year study. Measuring three or four times would have
been better, Evans said.
Grodstein said her group would continue tracking the women to see if the same
patterns hold true over time. "That would certainly make us feel more confident,
that this wasn't just a one-time thing," she said.
Given the difficulty of testing this type of hypothesis in a randomized,
double-blind study, this new information is about as good as researchers are
going to get, Grodstein said.
"Alcohol has important individual and societal risks, so you want to be
pretty cautious," she added. "But for those people who are comfortable that they
can stay at pretty low levels of drinking, there did seem to be some benefits in
terms of memory."