Fibrous Histiocytoma-like Spindle-Cell Proliferation in the Nipple After Body-Piercing.
Reported, January 11, 2012
We report the case of a 19-year-old pregnant woman who presented with a nipple tumor. The lesion consisted in a spindle-cell proliferation with histologic features similar to those of fibrous histiocytoma, with a highly vascularized stroma. Although it showed low mitotic activity, scattered marked atypical cells with prominent nucleoli were identified, thus raising concern about the benign nature of the tumor. Immunohistochemical evaluation revealed that the spindle cells were diffusely positive for vimentin, focally positive for CD68, and negative for all the other tested antibodies. The patient had a total excision of the lesion and she is free of disease after 30 months. To our knowledge this is the first reported case of a lesion of this type in the nipple after body-piercing.
Credits:Castillo M, Sanjuán A, Pérez N, Zanón G, Bons N, Vilanova M, Vanrell JA, Merino MJ, Fernández PL.
Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, Andorra, Spain.
More information at:
http://www.ncbi.nlm.nih.gov/pubmed/16501844
