Genes responsible for hearing loss
Reported November 15, 2007
WASHINGTON: A new study of twins has revealed that genes play a significant role in the level of hearing loss that often appears in late middle age.
Researchers from the Brandeis University examined genetic and environmental factors affecting hearing loss in the frequency range of speech recognition.
This research confirms the importance of genetic factors in age-associated hearing loss, and the need for vulnerable individuals and their families to take extra care to prevent further hearing damage, said lead author Brandeis neuroscientist Arthur Wingfield.
The study has recommended that middle-aged and older people with a genetic vulnerability to hearing loss should be particularly careful about environmental risk factors such as harmful noise and medications whose side-effects could be detrimental to hearing.
For the study, researchers examined 179 identical and 150 fraternal male twin pairs, ranging in age from 52 to 60 years, as part of the Viet Nam Era Twin Study of Aging (VETSA).
About two-thirds of the hearing loss in the individual subjects better ears could be accounted for by genetic factors. In the subjects poorer ears, about one-half of the hearing loss was due to genes, the study showed.
Wingfield said that even mild hearing loss can indirectly lead to declines in cognitive performance because intellectual energy normally reserved for higher-level comprehension must be directed toward perceptual effort for accurately hearing speech.
Hearing loss is the third most common chronic disability among older adults after arthritis and hypertension. The study is published in the Journal of Gerontology: Medical Sciences.
