Unexplained rapid weight loss in older people could be a sign of underlying disease and can be linked with increased risk of falls and fractures, as well as a poorer long-term prognosis. The understanding of factors that could contribute to rapid weight loss remains poor, with current treatments including correcting suboptimal dietary and physical activity behaviors. New … [Read more...]
New Weight Loss Medication may help Lower Blood Pressure in Adults with Obesity
The new weight loss medication tirzepatide significantly lowered the systolic blood pressure (the top number in a blood pressure reading) for nearly 500 adults with obesity who took the medication for about eight months, according to new research published today in Hypertension, an American Heart Association journal. Systolic blood pressure, or the top number in the blood … [Read more...]
Hand-Held Biosensor Makes Breast Cancer Screening Fast, Affordable, And Accurate
Breast cancer is on the rise, but new tools for early detection could save lives. In Journal of Vacuum Science & Technology B, by AIP Publishing, researchers from the University of Florida and National Yang Ming Chiao Tung University in Taiwan reported successful results from a hand-held breast cancer screening device that can detect breast cancer biomarkers from a … [Read more...]
Non-Invasive Techniques to Detect Skin Cancer
A study conducted by Aston University researchers has demonstrated that the appearance of ageing skin looks noticeably different compared to younger skin, when examined under polarised laser light. The scientists believe that their new finding could pave the way for new, non-invasive light-based techniques to detect diseases, including cancer, in older individuals. This … [Read more...]
Key to Healing Injured Hearts
A groundbreaking scientific study published in Nature Cardiovascular Research has unveiled a remarkable discovery that may have far-reaching implications for the treatment of heart disease. The intensive investigations utilizing single-cell genomics and genetic experiments were conducted by a team of scientists in theCardiomyocyte Renewal Laboratory and McGill Gene Editing … [Read more...]
Cold Water Swimming Improves Menopause Symptoms
Menopausal women who regularly swim in cold water report significant improvements to their physical and mental symptoms, finds a new study led by UCL researchers. The research, published in Post Reproductive Health, surveyed 1114 women, 785 of which were going through the menopause, to examine the effects of cold water swimming on their health and wellbeing. The findings … [Read more...]
New Model Predicts How Shoe Properties Affect a Runner’s Performance
A good shoe can make a huge difference for runners, from career marathoners to couch-to-5K first-timers. But every runner is unique, and a shoe that works for one might trip up another. Outside of trying on a rack of different designs, there's no quick and easy way to know which shoe best suits a person's particular running style. MIT engineers are hoping to change that with … [Read more...]
Furry fruit improves mental health — fast
Kiwifruit has proven itself as a powerful mood booster and new research from the University of Otago has shown just how fast its effects can be. In a study, published in The British Journal of Nutrition, researchers found the furry fruit improved vitality and mood in as little as four days. Co-author Professor Tamlin Conner, of the Department of Psychology, says the … [Read more...]
Women Exposed to Toxic Metals may Experience Earlier Aging of Their Ovaries
Middle-aged women who are exposed to toxic metals may have fewer eggs in their ovaries as they approach menopause, according to new research published in The Journal of Clinical Endocrinology & Metabolism. Diminished ovarian reserve is when women have fewer eggs compared to others their age. The condition may be linked to health problems such as hot flashes, weak … [Read more...]
Researchers Discover a New Role for a Protein that helps form Memories
The protein normally performs necessary housekeeping in the brain's hippocampus by working as part of a larger protein complex called the proteasome to destroy other proteins. But researchers in the College of Agriculture and Life Sciences' School of Animal Sciences recently noticed this protein, called RPT6, behaving in a previously undetected way. "We found that RPT6 is … [Read more...]
Physical Exercise Boosts Motor Learning and Remembering What one has Learned
Before a violinist tunes their instrument or surgeon stands at the training table to learn the skills needed for a new symphony or surgical procedure, they might consider heading out for a bike ride or run. Once they've practiced the new skill, there's good reason to put on their workout attire again. Indeed, being physically active and elevating one's heart rate has the … [Read more...]
Main Regulator for the Body’s ‘Oven’ Discovered
Obesity is defined as a pathological increase in white fat, and has become a major problem worldwide, with a greatly increased risk of cardiovascular diseases such as heart attack and stroke. "Exercise and dieting are not enough to effectively and permanently shed the pounds," says corresponding author Prof. Alexander Pfeifer, Director of the Institute of Pharmacology and … [Read more...]
Dietary Restriction Slows Brain Aging and Increases lifespan
Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Buck scientists have uncovered a role for a gene called OXR1 that is necessary for the lifespan extension seen with dietary restriction and is essential for healthy brain aging. "When people restrict the … [Read more...]
Reduced Blood Lead Levels Linked to Lower Blood Pressure
Through the Strong Heart Family Study, National Institutes of Health-supported researchers found that small declines in blood lead levelswere associated with long-term cardiovascular health improvements in American Indian adults. Participants who had the greatest reductions in blood lead levels saw their systolic blood pressure fall by about 7 mm Hg, an amount comparable to the … [Read more...]
Why Cancer Immunotherapies don’t Work for Everyone
Why cancer immunotherapies don't work for everyone (cancer) The study, published in the peer-reviewed journal Cell Reports, sheds light on why immunotherapy treatments don't work for all people or all diseases. For example, certain types of cancers -- including colon, pancreatic, prostate and brain cancers -- have stubbornly resisted immunotherapy. And while breast, … [Read more...]
Artificial Intelligence and Immunity
Researchers from Cleveland Clinic and IBM have published a strategy for identifying new targets for immunotherapy through artificial intelligence (AI). This is the first peer-reviewed publication from the two organizations' Discovery Accelerator partnership, designed to advance research in healthcare and life sciences. The team worked together to develop supervised and … [Read more...]
However, Adults Hardly have any Brown Fat, and it can be Found Mainly in Young and Slim People.
"We therefore asked how brown fat mass can be increased while simultaneously reducing bad white fat," says Bonn postdoctoral researcher and first author Dr. Laia Reverte-Salisa. Together with researchers from the University Medical Center Hamburg-Eppendorf, Helmholtz Munich and the University of Toulouse-Paul Sabatier, the Bonn team investigated the cAMP signaling pathway in … [Read more...]
Different Pain Types in Multiple Sclerosis can Cause Difficulty Ataying Active
For patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. Due to different causes of chronic pain though, physical exercise can be more difficult for some. Research published in the Journal of Pain from the University of Michigan found that widespread pain with nociplastic features, also known as WPNF, can make engaging in physical … [Read more...]
Main Regulator for the Body`s ‘oven’ Discovered
Brown fat cells convert energy into heat -- a key to eliminating unwanted fat deposits. In addition, they also protect against cardiovascular diseases. Researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Area "Life & Health" at the University of Bonn have now identified the protein EPAC1 as a new pharmacological target to increase brown … [Read more...]
Algae as a Surprising Meat Alternative and Source of Environmentally Friendly Protein
With more of us looking for alternatives to eating animals, new research has found a surprising environmentally friendly source of protein -- algae. The University of Exeter study has been published in The Journal of Nutrition and is the first of its kind to demonstrate that the ingestion of two of the most commercially available algal species are rich in protein which … [Read more...]
Survey Participants Who were Controlling Their Type 2 Diabetes ate Fewer Sugary Foods and Snacked Less Overall than Participants Without Diabetes and Those Whose Blood Sugar Levels Indicated They Were Prediabetic.
"Diabetes education looks like it's working, but we might need to bump education back to people who are at risk for diabetes and even to people with normal blood glucose levels to start improving dietary behaviors before people develop chronic disease," Taylor said. The study was published recently in PLOS Global Public Health. Researchers analyzed data from 23,708 U.S. … [Read more...]
Participants in School-Based Gardening and Food Programs Benefit From Lasting Impacts on Dietary Behaviors
To encourage fruit and vegetable consumption among youth, experiential food education programs such as gardening and cooking lessons have increased across both community and school settings. A recent research article in the Journal of Nutrition Education and Behavior, published by Elsevier, revealed how this early learning positively influenced food decisions as children grew … [Read more...]
US Adults Eat a Meal’s Worth of Calories of Snacks in a Day
Snacks constitute almost a quarter of a day's calories in U.S. adults and account for about one-third of daily added sugar, a new study suggests. Researchers analyzing data from surveys of over 20,000 people found that Americans averaged about 400 to 500 calories in snacks a day - often more than what they consumed at breakfast - that offered little nutritional … [Read more...]
Study Charts Possibilities for a Better way to Diagnose Gestational Diabetes
Pregnancy weight and biochemical markers measured in blood from women with gestational diabetes mellitus (GDM) were related to increased risk of poor pregnancy outcomes, suggesting a new direction for precision diagnostics, according to researchers. The study led by Ellen C. Francis, an assistant professor in the Department of Biostatistics and Epidemiology at Rutgers School … [Read more...]
Epigenetic Therapy Shows Promise for Endocrine-Resistant Breast Cancer
Using a low dose of the epigenetic therapy drug decitabine, which is currently used to treat some blood cancers, the researchers significantly suppressed the growth of endocrine-resistant breast tumours in mice and increased survival time by 90%. The finding, which will be tested in a future Phase I clinical trial, is a potential gamechanger for the more than 4,000 people who … [Read more...]
Study Unveils a Role of Mitochondria in Dietary Fat Processing
The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive amounts of fatty foods contributes to metabolic diseases such as obesity and atherosclerosis, fat is an indispensable component of our diet. Digested lipids supply the body with essential building blocks and facilitate the absorption of important vitamins. In a new study … [Read more...]
Large-Scale Study Uncovers Modifiable Risk Factors For Young-Onset Dementia
Researchers have identified a wide range of risk factors for young-onset dementia. The findings challenge the notion that genetics are the sole cause of the condition, laying the groundwork for new prevention strategies. The largescale study identified 15 risk factors, which are similar to those for late-onset dementia. For the first time, they indicate that it may be … [Read more...]
Study: Cuddling During Sleep Comes at a Cost, Even for Mice
If you’re having trouble sleeping, perhaps contact with a bedmate is causing the problem, say University of Michigan researchers. Ada Eban-Rothschild, assistant professor in U-M’s Department of Psychology, and colleagues tracked the sleep behavior of mice while in a social context. They noticed that these small rodents seek physical contact prior to sleep initiation and … [Read more...]
Elevated Pregnancy Blood Pressure may Leave Lasting Marks on the Heart
New research from the Smidt Heart Institute at Cedars-Sinai found that women who developed signs of elevated blood pressure during pregnancy were more likely to have residual evidence of abnormal heart structure and function up to a decade after the pregnancy. "This study helps to clarify that, for some women, pregnancy is not just a 'stress test' that unmasks underlying … [Read more...]
Dietary Shifts to Less Processed Foods Significantly Lower Triglycerides in Women
During reproductive age, poor nutrition quality increases obesity rates and, as a result, the risk of cardiovascular disease (CVD) and type 2 diabetes. Dyslipidemia also impacts health, particularly among women with polycystic ovary syndrome (PCOS). In pregnant women, elevated triglycerides increase the risk of gestational diabetes, which can lead to type 2 diabetes and CVD … [Read more...]
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