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One Dose of HPV Vaccine Enough?
– Reported, November 06 2013
(Ivanhoe Newswire) According to a recent study, women vaccinated with one dose of a human papillomavirus (HPV) vaccine had antibodies against the viruses that remained stable in their blood for four years, suggesting that a single dose of vaccine may be sufficient to generate long-term immune responses and protection against new HPV infections, and ultimately cervical cancer.
For the study, researchers looked for the presence of an immune response to the vaccine in blood samples drawn from 78, 192, and 120 women who received one, two, and three doses of the vaccine. They compared the results with data from 113 women who did not receive vaccination, but had antibodies against the viruses in their blood because they were infected with HPV in the past.
The researchers found that 100 percent of the women in all three groups had antibodies against HPV 16 and 18 in their blood for up to four years. Our findings challenge previous dogma that protein subunit vaccines require multiple doses to generate long-lived responses, Mahboobeh Safaeian, PhD, an investigator in the Division of Cancer Epidemiology and Genetics at the National Cancer Institute (NCI) in Bethesda, Md., was quoted as saying.
For more information, go to: http://www.aacr.org/
SOURCE: Cancer Prevention Research, November 2013
