Cancer

Doctors and scientists at Intermountain Medical Center in Salt Lake City printed and used a 3D kidney to help save a patient's organ during a complicated tumor-removal procedural. The 3D-printed model allowed doctors to study the patient's kidney in 3D to determine how to best remove the tumor as it was located in a precarious location adjacent to vital arteries and … [Read more...]

Tumors are composed of many subpopulations of cells. A general consensus among scientists is that these subpopulations are due to random mutations. However, Moffitt Cancer Center researchers found that these assumptions may be incorrect. In a new article published in the journal Cancer Research, they report that certain subpopulations can be predicted and do not develop … [Read more...]

Drinking piping hot coffee, tea and the caffeine-infused beverage yerba mate probably causes cancer, the World Health Organization announced Wednesday. Beverages surpassing 149 degrees Fahrenheit (65 degrees Celsius) may increase the risk of tumors in the esophagus, which resides in the chest area below the throat, according to USC's Mariana Stern and 22 other scientists … [Read more...]

The UK Lung cancer screening trial (UKLS) has been successfully completed and demonstrated that patients with a high risk of developing lung cancer can be identified with early stage disease and have up to a 73% chance of surviving for five years or more. The UKLS trial was conducted by experts in the University of Liverpool. The UKLS was undertaken in partnership with … [Read more...]

In a randomized Phase III study of the drug inotuzumab ozogamicin, a statistically significant percentage of patients with acute lymphoblastic leukemia (ALL) whose disease had relapsed following standard therapies, qualified for stem cell transplants. Inotuzumab ozogamicin, also known as CMC-544, links an antibody that targets CD22, a protein found on the surface of more … [Read more...]

Testing cancers for 'addiction' to a gene that boosts cell growth can pick out patients who may respond to a targeted drug under development, a major new study reports. By measuring the number of copies of just one gene from cancer DNA circulating in the bloodstream, scientists were able to identify the patients with stomach cancer who were most likely to respond to … [Read more...]

Researchers at the University of Rochester Wilmot Cancer Institute discovered something simple and inexpensive to reduce neuropathy in hands and feet due to chemotherapy--exercise. The study, involving more than 300 cancer patients, is to be presented this weekend and honored as a "Best of ASCO" among 5,800 abstracts at the world's largest gathering of oncologists, the … [Read more...]

Drugs to treat cancer and Alzheimer's disease usually target the active sites of specific protein molecules sustaining the disease. Traditional drug design views proteins as rigid 3-D objects with active sites consisting of surface-accessible "pockets" with a specific, well-defined structure. Traditional drug design involves finding small molecules with shapes that fit … [Read more...]

A study of almost 150,000 men from 8 European countries, presented at this year's European Obesity Summit (Gothenburg, 1-4 June) shows that higher body mass index (BMI) and waist circumference are associated with an increased risk of aggressive prostate cancer. This analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC) is by Dr Aurora … [Read more...]

Cancer researchers in Würzburg, in cooperation with the international Cancer Genome Atlas Research Network, have identified new genetic drivers of adrenal cancer. Würzburg was the center of coordination of the European scientists. Research teams from 39 institutions in Europe, Northern America, Southern America and Australia have collected and examined 91 adrenal cancer … [Read more...]

Experts at the U.S. National Institutes of Health are questioning the validity of a widely reported study in rats that linked cellphone radiation to tumors. The study, released Friday by the federal government's National Toxicology Program (NTP), found "low incidences" of two types of tumors in male rats exposed to the type of radio frequencies emitted by cellphones, the … [Read more...]

While breast cancer is the most common cause of cancer death in women worldwide, ovarian cancer also is a significant source of mortality as the fifth leading cause of cancer death among women. These facts reflect the continued need for further understanding and innovation in cancer treatment. A new study published in the International Journal of Molecular Sciences, … [Read more...]

Among nearly 35,000 initially healthy women who were followed-up for about 20 years, those with new-onset atrial fibrillation had an increased risk of cancer, according to a study published online by JAMA Cardiology. Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with an increased risk of major cardiovascular complications. A substantial … [Read more...]

Research revealing early changes at epigenetic level points to possible new prevention strategies for ovarian cancer The discovery of early changes in the cells of the Fallopian tubes of women carrying the BRCA genetic mutation could open the way for new preventative strategies for ovarian cancer, reducing the need for invasive surgery, according to research published in … [Read more...]

A large proportion of cancer cases and deaths among U.S. individuals who are white might be prevented if people quit smoking, avoided heavy drinking, maintained a BMI between 18.5 and 27.5, and got moderate weekly exercise for at least 150 minutes or vigorous exercise for at least 75 minutes, according to a new study published online by JAMA Oncology. Cancer is a leading … [Read more...]

Having survived cancer as a child does not necessarily have a ripple effect that makes people lead a healthier lifestyle once they grow up. In fact, in a report derived from a National Cancer Institute-funded study of childhood cancer survivors known as the Chicago Healthy Living Study, investigators found that childhood cancer survivors in no way adhere more closely to … [Read more...]

Female cancer patients of reproductive age could preserve their fertility during radiation and chemotherapy through treatments that target the DNA damage response in oocytes (the cells that develop into eggs), an approach that works in animal models. Jackson Laboratory Assistant Professor Ewelina Bolcun-Filas, Ph.D., and Terri L. Woodward, M.D., assistant professor at the … [Read more...]

Horseradish contains cancer-fighting compounds known as glucosinolates. Glucosinolate type and quantity vary depending on size and quality of the horseradish root. For the first time, the activation of cancer-fighting enzymes by glucosinolate products in horseradish has been documented. The humble horseradish may not be much to look at, but a recent University of Illinois … [Read more...]

A multi-center study led by Fred Hutchinson Cancer Research Center has found that high-dose supplementation with both the trace element selenium and vitamin E increase the risk of high-grade prostate cancer. But importantly, this risk depends upon a man's selenium status before taking the supplements. These findings, published in Journal of the National Cancer Institute, are … [Read more...]

According to recent studies, the U.S. has a disadvantage in women's life expectancy compared to peer countries despite high rates of health screenings such as mammography and popular national awareness campaigns. Recently, researchers at the University of Missouri examined the perceptions of risk among females and found that minority and less educated women believe that breast … [Read more...]

A team from the International School for Advanced Studies (SISSA) in Trieste has obtained very promising results by applying gene therapy to glioblastoma. Tests in vitro and in vivo on mice provided very clear-cut results, and modelling demonstrates that the treatment targets at least six different points of tumour metabolism. Gene therapy, a technique that selectively attacks … [Read more...]

Firefighters face many risks during their jobs, but, ironically, the most dangerous part of running into a burning building isn’t the flames, it’s the smoke. It billows off furniture, appliances and carpets in toxic waves of cancer-causing fumes. That’s how about 60 percent of career firefighters will die, according to the international association of fire fighters. Cancer has … [Read more...]

Despite studies that claim people with cancer are less likely to develop Alzheimer's disease--raising the possibility that what triggers cancer also prevents the neurodegenerative disorder--a new investigation finds a more somber explanation. Many cancer patients don't live long enough to get Alzheimer's. The research, led by investigators at Huntsman Cancer Institute at the … [Read more...]

A new study has found that following a healthy lifestyle may lower childhood cancer survivors' risk of developing the metabolic syndrome. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings indicate that children with cancer and adults who had cancer when they were children should receive information about how their lifestyle … [Read more...]