PFAS are a group of more than 4,700 synthetic chemicals, first developed in the 1940s and which are widely used in industry as well as in consumer products such as non-stick cookware, water and stain-repellent coatings, food packaging, carpeting, firefighting foam, and even cosmetics. Their molecular structure is based on a linked chain of carbon atoms with one or more fluorine … [Read more...]
Treatment Prevents Hypoglycemia in Children with Hyperinsulinism
There are currently very few medical treatments for HI, and those treatments are of limited effectiveness while also associated with significant side effects," said senior study author Diva D. De León-Crutchlow, MD, Chief of the Division of Endocrinology and Diabetes and Director of the Congenital Hyperinsulinism Center at Children's Hospital of Philadelphia. "We are very … [Read more...]
Plant-Based Omega-3s May Boost Heart Health, Reduce Risk of Heart Disease
In a comprehensive literature review, the researchers found that consuming ALA that is found in plant-based foods like walnuts and flaxseeds was associated with a 10% lower risk of cardiovascular disease and a 20% reduced risk of fatal coronary heart disease. Penny Kris-Etherton, Evan Pugh University Professor of Nutritional Sciences at Penn State, said the review suggests … [Read more...]
Scientists Develop Coated Probiotics that could be Effectively Delivered into the Human Gut
Probiotics are defined by the World Health Organisation as live microorganisms, which when administered in adequate amounts, confer a health benefit on the host[1]. They have been shown to help prevent infections of the urinary and digestive tracts, and to maintain a healthy gut flora, which is linked to reducing the risk of obesity and promoting overall … [Read more...]
Exercise Holds Even More Heart Health Benefits for People with Stress-Related Conditions
The research findings add to mounting evidence that exercise improves cardiovascular health by helping to activate parts of the brain that counteract stress. Overall, the study found that people who achieved the recommended amount of physical activity per week were 17% less likely to suffer a major adverse cardiovascular event than those who exercised less. These benefits were … [Read more...]
COVID-19 Infection Linked to Higher Risk of Neuropathy
In a study of more than 1,500 people who were tested for SARS-CoV-2 during the first year of the pandemic, the researchers found that those who tested positive for the virus were about three times more likely to report pain, numbness or tingling in their hands and feet as those with negative tests. The findings are reported online March 24 in the journal Pain. "Several … [Read more...]
New Study Reveals Why HIV Remains in Human Tissue Even After Antiretroviral Therapy
Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system. Now, new research by University of Alberta immunologist … [Read more...]
A Novel Painless and Reliable Allergy Test
Approximately one third of the world's population suffers from one or more allergies, with the trend increasing every year. By far the most widespread form of allergy is the so-called type I allergy, also known as immediate-type allergy. This includes, for example, allergic rhinitis (hay fever), allergic asthma, food allergies, or allergies against insect venoms, pollen, … [Read more...]
Researchers Studying Ways to Ease Asthma Symptoms Caused by Seasonal Allergies
"Asthma has no cure and current treatments primarily focus on resolving the symptoms," said Ben Ulrich, PhD, lead author of the study. "While spending time in the high-risk asthma clinic at Riley Hospital for Children, I observed many patients had a more intermittent disease course. We went into the lab and developed models to more accurately define allergic memory and recall … [Read more...]
Exercise Post-Vaccine Bumps up Antibodies, New Study Finds
Researchers at Iowa State University found 90 minutes of mild- to moderate-intensity exercise directly after a flu or COVID-19 vaccine may provide an extra immune boost. In the newly published study, participants who cycled on a stationary bike or took a brisk walk for an hour-and-a-half after getting a jab produced more antibodies in the following four weeks compared to … [Read more...]
Eating Prunes may Help Protect against bone loss in older women
It's already well known that prunes are good for your gut, but new Penn State research suggests they may be good for bone health, too. In a research review, the researchers found that prunes can help prevent or delay bone loss in postmenopausal women, possibly due to their ability to reduce inflammation and oxidative stress, both of which contribute to bone loss. "In … [Read more...]
A Serendipitous Finding Lends New Insight into How Atopic Dermatitis Develops
Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a new study pinpoints a cascade of inflammatory signaling that precedes the appearance of skin ulcers, shedding light on the early stages of the condition and identifying potential … [Read more...]
How Migraine Pain Signals are Generated, and Blocked
An international team of researchers has discovered that Schwann cells -- which are abundant in the peripheral nervous system and create a protective sheath around nerve fibers -- play an essential role in migraine pain. Their study, conducted in mice and human Schwann cells and published in Nature Communications, illustrates how pain is signaled from within Schwann cells and … [Read more...]
Overlooked Disease: Tens of Thousands of People have Problems at work
Imagine your head pounding. And when you try to move, a door slams, or curtains are drawn it gets much worse. Ideally, you would like to crawl under your blanket in a dark and quiet room. This is how it may feel for people suffering from migraine or frequent tension headaches. Untreated, a migraine attack may last for 4-72 hours, and tension headaches may potentially last … [Read more...]
Highly Responsive Immune Cells Seem to be Beneficial For The Brain
Findings by researchers from Germany support the view that hyperactive immune cells in the brain can have a protective effect in the course of neurodegenerative diseases. Experts from Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Ludwig-Maximilians-Universität München (LMU) and LMU Klinikum München report on this in the scientific magazine The EMBO Journal. The … [Read more...]
New Clues in the Brain Linking Pain and Food
It has long been known that there is an association between food and pain, as people with chronic pain often struggle with their weight. Researchers at the Del Monte Institute for Neuroscience may have found an explanation in a new study that suggests that circuitry in the brain responsible for motivation and pleasure is impacted when someone experiences pain. "These findings … [Read more...]
New Method for Stimulating Signaling to Improve Metabolic Health and Possibly Treat Obesity
Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors … [Read more...]
First get your heart in shape then get pregnant
This Valentine's Day, a new Northwestern Medicine study shines a spotlight on an important but often overlooked matter of the heart -- optimizing one's cardiovascular health before getting pregnant. More than one in two young women between the ages of 20 and 44 who gave birth in the United States in 2019 had poor heart health before becoming pregnant, the study found. Poor … [Read more...]
Vaccinated Women Pass COVID-19 Antibodies to Breastfeeding Babies, Study Finds
Women vaccinated against COVID-19 transfer SARS-CoV-2 antibodies to their breastfed infants, potentially giving their babies passive immunity against the coronavirus, according to University of Massachusetts Amherst research. The study, published in the journal Obstetrics & Gynecology, measured the immune response to the COVID-19 mRNA vaccine in both breast milk and the … [Read more...]
Infants with low-risk Deliveries should not Need Antibiotics at Birth, Study Suggests
Infants born via uncomplicated cesarean delivery, without labor or membrane rupture before delivery and no concern for infection, should not need antibiotics at birth, according to a study by researchers at Children's Hospital of Philadelphia (CHOP). The findings, which were published today in Pediatrics, could help clinicians tailor the use of early antibiotics in newborns. … [Read more...]
COVID-19 linked to Complications During Pregnancy, Study Finds
Women who have Covid-19 towards the end of their pregnancy are vulnerable to birth-related complications. They are more likely to have complications than those who get Covid-19 in the earlier stages of pregnancy or who haven't had Covid-19 at all. The findings show that preterm births, stillbirths and newborn deaths are more common among women who have the virus 28 … [Read more...]
New Target may Help Protect Bones as We Age
Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one. They are finding that in aging bone, the mineralocorticoid receptor, better known for its role in blood pressure regulation, is a key factor in bone health, says Dr. Meghan E. … [Read more...]
Discovery could Hold the Key to Alleviating Metabolic Disease
Scientists have long sought to find out how some diseases can have symptoms restricted to just one tissue when they are caused by a single faulty protein found throughout the body. Familial Partial Lipodystrophy type 2 (FPLD2) is a rare disorder causing diabetes, loss of fat in the arms and legs and over development of muscles, yet the faulty protein, lamin A, is found in … [Read more...]
Coffee and Tea Drinking may be Associated with Reduced Rates of Stroke and Dementia
Drinking coffee or tea may be associated with a lower risk of stroke and dementia, according to a study of healthy individuals aged 50-74 publishing Nov. 16 in the open-access journal PLOS Medicine. Drinking coffee was also associated with a lower risk of post-stroke dementia. Strokes are life-threatening events which cause 10 percent of deaths globally. Dementia is a … [Read more...]
Repeated Exposure to Major Disasters has long-term Mental Health Impacts
Repeated exposure to major disasters does not make people mentally stronger, a recent study from the Texas A&M University School of Public Health found: individuals who have been repeatedly exposed to major disasters show a reduction in mental health scores. Additionally, the research team found that the more experience the individuals had with such events, the lower … [Read more...]
How a Newly Approved Antibody Treatment Can Help People Who Can’t Get COVID-19 Vaccines
There’s a new tool in the fight against COVID-19, but it’s not a vaccine. An antibody combination drug known as Evusheld has receivedTrusted Source an emergency use authorization from the Food and Drug Administration (FDA) to help prevent COVID-19 in some adults and children over the age of 12 who are at least 88 pounds. Under this therapy, a person receives two … [Read more...]
Microglial Methylation ‘Landscape’ in Human Brain
In the central nervous system, microglial cells play critical roles in development, aging, brain homeostasis, and pathology. Recent studies have shown variation in the gene-expression profile and phenotype of microglia across brain regions and between different age and disease states. But the molecular mechanisms that contribute to these transcriptomic changes in the human … [Read more...]
How Regular Exercise can Protect Against Fatty Liver Associated Diseases
Exercise not only trains the muscles but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research (DZD), Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in particular of the liver mitochondria, can be observed in this process. The study has now been published in Molecular … [Read more...]
For some Greenlanders, Eating Sugar is Healthy
Imagine being able to swap out broccoli for sweets, Ben & Jerry's or some other sugary treat and achieve the same health benefits. This is fact not fantasy for about two to three percent of the Greenlandic population. Two copies of a gene variant make it so that they absorb sugar differently than other people do. "Adult Greenlanders with the genetic variation have … [Read more...]
Dietary Fiber Improves Outcomes for Melanoma Patients on Immunotherapy
Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration that includes the Oregon State University College of Pharmacy. Published today in Science, the study led by the University of Texas and the National … [Read more...]
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