Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a new study pinpoints a cascade of inflammatory signaling that precedes the appearance of skin ulcers, shedding light on the early stages of the condition and identifying potential … [Read more...]
How Migraine Pain Signals are Generated, and Blocked
An international team of researchers has discovered that Schwann cells -- which are abundant in the peripheral nervous system and create a protective sheath around nerve fibers -- play an essential role in migraine pain. Their study, conducted in mice and human Schwann cells and published in Nature Communications, illustrates how pain is signaled from within Schwann cells and … [Read more...]
Overlooked Disease: Tens of Thousands of People have Problems at work
Imagine your head pounding. And when you try to move, a door slams, or curtains are drawn it gets much worse. Ideally, you would like to crawl under your blanket in a dark and quiet room. This is how it may feel for people suffering from migraine or frequent tension headaches. Untreated, a migraine attack may last for 4-72 hours, and tension headaches may potentially last … [Read more...]
Highly Responsive Immune Cells Seem to be Beneficial For The Brain
Findings by researchers from Germany support the view that hyperactive immune cells in the brain can have a protective effect in the course of neurodegenerative diseases. Experts from Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Ludwig-Maximilians-Universität München (LMU) and LMU Klinikum München report on this in the scientific magazine The EMBO Journal. The … [Read more...]
New Clues in the Brain Linking Pain and Food
It has long been known that there is an association between food and pain, as people with chronic pain often struggle with their weight. Researchers at the Del Monte Institute for Neuroscience may have found an explanation in a new study that suggests that circuitry in the brain responsible for motivation and pleasure is impacted when someone experiences pain. "These findings … [Read more...]
New Method for Stimulating Signaling to Improve Metabolic Health and Possibly Treat Obesity
Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors … [Read more...]
First get your heart in shape then get pregnant
This Valentine's Day, a new Northwestern Medicine study shines a spotlight on an important but often overlooked matter of the heart -- optimizing one's cardiovascular health before getting pregnant. More than one in two young women between the ages of 20 and 44 who gave birth in the United States in 2019 had poor heart health before becoming pregnant, the study found. Poor … [Read more...]
Vaccinated Women Pass COVID-19 Antibodies to Breastfeeding Babies, Study Finds
Women vaccinated against COVID-19 transfer SARS-CoV-2 antibodies to their breastfed infants, potentially giving their babies passive immunity against the coronavirus, according to University of Massachusetts Amherst research. The study, published in the journal Obstetrics & Gynecology, measured the immune response to the COVID-19 mRNA vaccine in both breast milk and the … [Read more...]
Infants with low-risk Deliveries should not Need Antibiotics at Birth, Study Suggests
Infants born via uncomplicated cesarean delivery, without labor or membrane rupture before delivery and no concern for infection, should not need antibiotics at birth, according to a study by researchers at Children's Hospital of Philadelphia (CHOP). The findings, which were published today in Pediatrics, could help clinicians tailor the use of early antibiotics in newborns. … [Read more...]
COVID-19 linked to Complications During Pregnancy, Study Finds
Women who have Covid-19 towards the end of their pregnancy are vulnerable to birth-related complications. They are more likely to have complications than those who get Covid-19 in the earlier stages of pregnancy or who haven't had Covid-19 at all. The findings show that preterm births, stillbirths and newborn deaths are more common among women who have the virus 28 … [Read more...]
New Target may Help Protect Bones as We Age
Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one. They are finding that in aging bone, the mineralocorticoid receptor, better known for its role in blood pressure regulation, is a key factor in bone health, says Dr. Meghan E. … [Read more...]
Discovery could Hold the Key to Alleviating Metabolic Disease
Scientists have long sought to find out how some diseases can have symptoms restricted to just one tissue when they are caused by a single faulty protein found throughout the body. Familial Partial Lipodystrophy type 2 (FPLD2) is a rare disorder causing diabetes, loss of fat in the arms and legs and over development of muscles, yet the faulty protein, lamin A, is found in … [Read more...]
Coffee and Tea Drinking may be Associated with Reduced Rates of Stroke and Dementia
Drinking coffee or tea may be associated with a lower risk of stroke and dementia, according to a study of healthy individuals aged 50-74 publishing Nov. 16 in the open-access journal PLOS Medicine. Drinking coffee was also associated with a lower risk of post-stroke dementia. Strokes are life-threatening events which cause 10 percent of deaths globally. Dementia is a … [Read more...]
Repeated Exposure to Major Disasters has long-term Mental Health Impacts
Repeated exposure to major disasters does not make people mentally stronger, a recent study from the Texas A&M University School of Public Health found: individuals who have been repeatedly exposed to major disasters show a reduction in mental health scores. Additionally, the research team found that the more experience the individuals had with such events, the lower … [Read more...]
How a Newly Approved Antibody Treatment Can Help People Who Can’t Get COVID-19 Vaccines
There’s a new tool in the fight against COVID-19, but it’s not a vaccine. An antibody combination drug known as Evusheld has receivedTrusted Source an emergency use authorization from the Food and Drug Administration (FDA) to help prevent COVID-19 in some adults and children over the age of 12 who are at least 88 pounds. Under this therapy, a person receives two … [Read more...]
Microglial Methylation ‘Landscape’ in Human Brain
In the central nervous system, microglial cells play critical roles in development, aging, brain homeostasis, and pathology. Recent studies have shown variation in the gene-expression profile and phenotype of microglia across brain regions and between different age and disease states. But the molecular mechanisms that contribute to these transcriptomic changes in the human … [Read more...]
How Regular Exercise can Protect Against Fatty Liver Associated Diseases
Exercise not only trains the muscles but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research (DZD), Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in particular of the liver mitochondria, can be observed in this process. The study has now been published in Molecular … [Read more...]
For some Greenlanders, Eating Sugar is Healthy
Imagine being able to swap out broccoli for sweets, Ben & Jerry's or some other sugary treat and achieve the same health benefits. This is fact not fantasy for about two to three percent of the Greenlandic population. Two copies of a gene variant make it so that they absorb sugar differently than other people do. "Adult Greenlanders with the genetic variation have … [Read more...]
Dietary Fiber Improves Outcomes for Melanoma Patients on Immunotherapy
Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration that includes the Oregon State University College of Pharmacy. Published today in Science, the study led by the University of Texas and the National … [Read more...]
Overactive Bladder and Urinary Incontinence Worsen with Age
If you're feeling more sudden urges to run to the bathroom as you age, you're not alone. A new study suggests postmenopausal women aged 45 to 54 years are more likely to have overactive bladder (OAB) syndrome. Additionally, obesity and multiple births put a woman at greater risk for stress urinary incontinence (SUI). Study results are published online today in Menopause, the … [Read more...]
Normal 6-Month Outcomes in Babies of Women With COVID-19 During Pregnancy
Babies born to women who had COVID-19 during pregnancy showed reassuring patterns of growth and development at 6-month follow-up, according to a study from Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern Medicine in partnership with Erie Family Health Center, a Federally Qualified Health Center (FQHC) that serves a diverse and low-income patient … [Read more...]
Clues to Treatment of Schizophrenia and Bipolar Disorder found in Recently Evolved Region of the ‘Dark Genome’
Scientists investigating the DNA outside our genes -- the 'dark genome' -- have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder. They say these new proteins can be used as biological indicators to distinguish between the two conditions, and to identify patients more prone to psychosis or suicide. Schizophrenia … [Read more...]
HIV Infection: Better Understanding The Reservoir of Virus in the Body
LMU researchers have developed a method that allows resting human immune cells to be genetically analyzed in detail for the first time. CD4+ T cells are important parts of the immune system and play a key role in defending the body against pathogens. As they possess a great variety of defense mechanisms against HIV in their resting state, they are infected only very rarely … [Read more...]
People With High-Risk Prediabetes Benefit From Intensive lifestyle Intervention
Intensive lifestyle intervention with plenty of exercise helps people with prediabetes improve their blood glucose levels over a period of years and thus delay or even prevent type 2 diabetes. In particular, individuals with prediabetes at highest risk benefited from intensive lifestyle intervention. This is shown by the evaluation of the Prediabetes Lifestyle Intervention … [Read more...]
Fermented Soybeans Suppress Asthma-Induced Airway Inflammation
Bronchial asthma causes symptoms such as wheezing and cough due to chronic airway inflammation, but there is no fundamental treatment for it, leaving a desire for new prevention and treatment methods. Now a new study reveals that a fermented soy product called ImmuBalance suppresses airway inflammation in animal models of asthma. Researchers from the Department of … [Read more...]
Latte Lovers Rejoice! Study Reveals Drinking Coffee could Lower the Risk of Alzheimer’s Disease
Good news for those of us who can't face the day without their morning flat white: a long-term study has revealed drinking higher amounts of coffee may make you less likely to develop Alzheimer's disease. As part of the Australian Imaging, Biomarkers and Lifestyle Study of ageing, researchers from Edith Cowan University (ECU) investigated whether coffee intake affected the … [Read more...]
How Eating Less in Early Life could help with Reproduction Later on
Switching from a restricted diet to eating as much as you like could be beneficial for reproduction in later life, according to new research from the University of East Anglia. Researchers studied the eating and mating habits of the small fruit fly Drosophila melanogaster. They found that females that consumed less food for their entire lives lived longer, however they … [Read more...]
Only Alcohol — Not Caffeine, Diet or Lack of Sleep — Might Trigger Heart Rhythm Condition
New research from UC San Francisco that tested possible triggers of a common heart condition, including caffeine, sleep deprivation and sleeping on the left side, found that only alcohol use was consistently associated with more episodes of the heart arrhythmia. The authors conclude that people might be able to reduce their risk of atrial fibrillation (AF) by avoiding … [Read more...]
‘Broken heart’ syndrome is on the rise in women
The study, published in the Journal of the American Heart Association (JAHA), suggests middle-aged and older women are being diagnosed with broken heart syndrome more frequently -- up to 10 times more often -- than younger women or men of any age. The research also suggests that the rare condition has become more common, and the incidence has been rising steadily since well … [Read more...]
Unraveling the mystery of why we overeat
Eating is one of life's greatest pleasures, and overeating is one of life's growing problems. In 2019, researchers from The Stuber Lab at the University of Washington School of Medicine discovered that certain cells light up in obese mice and prevent signals that indicate satiety, or feeling full. Now comes a deeper dive into what role these cells play. A study … [Read more...]
- « Previous Page
- 1
- …
- 14
- 15
- 16
- 17
- 18
- …
- 426
- Next Page »
