Brain changes in people with Alzheimer's disease and in those with mild traumatic brain injuries (TBIs) have significant similarities, a new USC study shows, suggesting new ways to identify patients at high risk for Alzheimer's. The findings appear this week in GeroScience. TBIs, which affect over 1.7 million Americans every year, are often followed by changes in brain … [Read more...]
Leg Muscle Action Assists Blood Flow Independently of Age
Chronic lower-limb edema (CLE) -- the permanent accumulation of fluid in the leg -- often occurs in elderly people. The condition leads to various physical and mental problems, including difficulty in walking or moving, fatigue and anxiety. One cause of CLE is the lack of physical activity, which is associated with a decrease in muscle pump action. The latter refers to the leg … [Read more...]
Poor Iodine Levels in Women Pose Risks to Fetal Intellectual Development in Pregnancy
An increasing number of young women are at increased risk of having children born with impaired neurological conditions, due to poor iodine intake. Dietary changes, including a growing trend towards the avoidance of bread and iodised salt, as well as a reduced intake of animal products containing iodine can contribute to low iodine levels. A small pilot study undertaken … [Read more...]
Skin and Bones Repaired by Bioprinting During Surgery
Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting during surgery, and their work may lead to faster and better methods of healing skin and bones. "This work is clinically significant," said … [Read more...]
Recreating the earliest stages of life
In their effort to understand the very earliest stages of life and how they can go wrong, scientists are confronted with ethical issues surrounding the use of human embryos. The use of animal embryos is also subject to restrictions rooted in ethical considerations. To overcome these limitations, scientists have been trying to recreate early embryos using stem cells. One of … [Read more...]
Skeletal Defects may be Ameliorated after Immobility in the Womb
Researchers from Trinity College Dublin have discovered that some skeletal defects associated with a lack of movement in the womb during early development may still be ameliorated after such periods of immobility if movement resumes. The researchers' discovery was made using chicken embryos, which develop similarly to their human equivalents and which can be easily viewed as … [Read more...]
More Belly Weight Increases Danger of Heart Disease even if BMI does not Indicate Obesity
People with abdominal obesity and excess fat around the body's mid-section and organs have an increased risk of heart disease even if their body mass index (BMI) measurement is within a healthy weight range, according to a new Scientific Statement from the American Heart Association published today in the Association's flagship journal, Circulation. "This scientific … [Read more...]
Muscle Gene Linked to Type 2 Diabetes
People with type 2 diabetes tend to have poorer muscle function than others. Now a research team at Lund University in Sweden has discovered that in type 2 diabetes, a specific gene is of great importance for the ability of muscle stem cells to create new mature muscle cells. The findings are published in Nature Communications. "In people with type 2 diabetes, the VPS39 gene … [Read more...]
DHA Supplement may Offset Impact of Maternal Stress on Unborn Males
Neurodevelopmental disorders like autism and schizophrenia disproportionately affect males and are directly linked to early life adversity caused by maternal stress and other factors, which might be impacted by nutrition. But the underlying reasons for these male-specific impacts are not well understood. Researchers from the University of Missouri School of Medicine and the MU … [Read more...]
Diets Rich in Nitrates from Vegetables Improve Muscle Function
Diets rich in nitrates from vegetables improve muscle function, according to a study published in the Journal of Nutrition. In 3,759 participants in the Australian Diabetes, Obesity, and Lifestyle Study (AusDiab), those with the highest nitrate consumption, mainly from vegetable sources, performed with more strength and speed in the physical tests when compared to those who ate … [Read more...]
Kids’ Metabolic Health can be Improved with Exercise During Pregnancy: here’s why
A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring. According to researchers, the key lies with a protein called SOD3, vitamin D and adequate exercise, with the outcomes possibly forming the first steps to designing rational diet and exercise programs to use during pregnancy and particularly when … [Read more...]
Parkinson’s, Cancer, Type 2 Diabetes Share a Key Element That Drives Disease
When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell's most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power stations that generate energy for the cell. Now Salk researchers have discovered a direct link between a master sensor of cell stress and Parkin itself. … [Read more...]
Artificial Intelligence Could ‘Crack The Language of Cancer and Alzheimer’s’
Powerful algorithms used by Netflix, Amazon and Facebook can 'predict' the biological language of cancer and neurodegenerative diseases like Alzheimer's, scientists have found. Big data produced during decades of research was fed into a computer language model to see if artificial intelligence can make more advanced discoveries than humans. Academics based at St John's … [Read more...]
Relieve Your Stress, Relieve Your Allergies
Increased allergic reactions may be tied to the corticotropin-releasing stress hormone (CRH), suggests a study published this month in the International Journal of Molecular Sciences. These findings may help clarify the mechanism by which CRH induces proliferation of mast cells (MC) -- agents involved in the development of allergies in the human nasal cavity. "In my daily … [Read more...]
Losing Weight Through Exercise
Why physical activity entices you to eat more - and how to fight it Worldwide 39 percent of the adults were overweight in 2016, according to statistics of the World Health Organization. In the US the prevalence of obesity was 42.4 percent in 2017/2018, according to a survey of the National Center for Health Statistics (NCHS). Concurrently millions of people want to lose … [Read more...]
Late Night Snacks May Hurt Your Workplace Performance, Study Finds
A recent study finds that unhealthy eating behaviors at night can make people less helpful and more withdrawn the next day at work. "For the first time, we have shown that healthy eating immediately affects our workplace behaviors and performance," says Seonghee "Sophia" Cho, corresponding author of the study and an assistant professor of psychology at North Carolina State … [Read more...]
Cells Burn More Calories After Just One Bout of Moderate Aerobic Exercise, OSU Study Finds
In a recent study testing the effects of exercise on overall metabolism, researchers at Oregon State University found that even a single session of moderate aerobic exercise makes a difference in the cells of otherwise sedentary people. Mitochondria are the part of the cell responsible for the biological process of respiration, which turns fuels such as sugars and fats into … [Read more...]
Evidence Supports COVID-19 Hearing Loss Link, Say Scientists
Hearing loss and other auditory problems are strongly associated with Covid-19 according to a systematic review of research evidence led by University of Manchester and NIHR Manchester Biomedical Research Centre (BRC) scientists. Professor Kevin Munro and PhD researcher Ibrahim Almufarrij found 56 studies that identified an association between COVID-19 and auditory and … [Read more...]
Eating Processed Meat Could Increase Dementia Risk, Researchers Say
Scientists from the University's Nutritional Epidemiology Group used data from 500,000 people, discovering that consuming a 25g serving of processed meat a day, the equivalent to one rasher of bacon, is associated with a 44% increased risk of developing the disease. But their findings also show eating some unprocessed red meat, such as beef, pork or veal, could be protective, … [Read more...]
Non-invasive Skin Swab Samples can Quickly Detect COVID-19, a New Study Finds
Researchers at the University of Surrey have found that non-invasive skin swab samples may be enough to detect COVID-19. The most widely used approach to testing for COVID-19 requires a polymerase chain reaction (PCR) test, which involves taking a swab of the back of the throat and far inside the nose. In a paper published by Lancet E Clinical Medicine, chemists from Surrey … [Read more...]
Exercise During Pregnancy may Save Kids from Health Problems as Adults
Exercise during pregnancy may let mothers significantly reduce their children's chances of developing diabetes and other metabolic diseases later in life, new research suggests. A study in lab mice has found that maternal exercise during pregnancy prevented the transmission of metabolic diseases from an obese parent -- either mother or father -- to child. If the finding holds … [Read more...]
For Better Migraine Treatment, Try Adding Some Downward Dogs
Adding yoga to your regularly prescribed migraine treatment may be better than medication alone, according to a study published in the May 6, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. The new research suggests yoga may help people with migraines have headaches that happen less often, don't last as long and are less … [Read more...]
Heritable Traits That Appear in Teen Years Raise Risk for Adult Cannabis Use
While some youth experiment with marijuana but don't go on to long-term use, others develop a problematic pot habit that continues into adulthood. A major new analysis shows that at least a small portion of the risk for developing into an adult marijuana user may be related to inherited behaviors and traits that appear during adolescence. The journal Addiction published the … [Read more...]
Physical Activity Helps Curb Low-grade Inflammation in Children
According to a recent Finnish study, accumulating more brisk and vigorous physical activity can curb adiposity-induced low-grade inflammation. The study also reported that diet quality had no independent association with low-grade inflammation. The findings, based on the ongoing Physical Activity and Nutrition in Children (PANIC) Study conducted at the University of Eastern … [Read more...]
Total Knee Replacement a Cost-Effective Treatment for Patients with Knee Osteoarthritis
Knee osteoarthritis is a painful condition that affects over 14 million U.S. adults, many of whom have extreme obesity, defined by body mass index (BMI) greater than 40kg/m2. Total knee replacement (TKR) is often recommended to treat advanced knee osteoarthritis, but surgeons may be hesitant to operate on patients with extreme obesity due to concerns about the increased risks … [Read more...]
Prolonged Immune Response may Contribute to Post-COVID-19 Blood Clots
Serious complications due to blood clots, such as heart attacks and strokes, that are experienced by some COVID-19 survivors may be caused by a lingering immune response in the blood vessels after recovery, suggests a study published today in eLife. The findings may help explain why some COVID-19 survivors, so-called 'long-haulers', report lasting COVID-19 symptoms or why some … [Read more...]
Bacteria may Aid Anti-Cancer Immune Response
Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. In a new study published in Nature, researchers at the Weizmann Institute of Science and their collaborators have discovered that the immune system "sees" these bacteria and shown they can be harnessed to provoke an immune reaction against the tumor. The study may also help … [Read more...]
BMI1, a Promising Gene to Protect Against Alzheimer’s Disease.
Another step towards understanding Alzheimer's disease has been taken at the Maisonneuve-Rosemont Hospital Research Centre. Molecular biologist Gilbert Bernier, and professor of neurosciences at Université de Montréal, has discovered a new function for the BMI1 gene, which is known to inhibit brain aging. The results of his work have just been published in Nature … [Read more...]
Satiety factor Associated with prolonged exercise
A drug that helps us to eat less could help the more than 650 million people around the world who live with obesity. One of the emerging drug candidates that interest researchers is the hormone GDF15 that, when given to rodents, lowers their appetite and body weight. New research from the University of Copenhagen finds that the body produces large amounts GDF15 during extended … [Read more...]
Pregnant women pass along protective COVID antibodies to their babies
Antibodies that guard against COVID-19 can transfer from mothers to babies while in the womb, according to a new study from Weill Cornell Medicine and NewYork-Presbyterian researchers published in the American Journal of Obstetrics and Gynecology. This discovery, published Jan. 22, adds to growing evidence that suggests that pregnant women who generate protective … [Read more...]
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