A team of researchers led by professor Jean-Christophe Marine (VIB-KU Leuven) has identified NEAT1, a non-coding RNA, as a potential therapeutic target in the fight against cancer. In collaboration with the Cédric Blanpain lab (ULB), VIB researchers have shown that NEAT1 plays an important role in the survival of highly dividing cells -- and in particular of cancer cells. These … [Read more...]
Eczema: Risks & Benefits of Frequent Bathing
If you have a child with newly-diagnosed eczema, you may be wondering how often you should bathe him. You are not alone. For more than 100 years, doctors have been asked about the risks and benefits of frequent bathing for those with atopic dermatitis (eczema). And parents haven't gotten consistent responses. A new article in Annals of Allergy, Asthma and Immunology, … [Read more...]
Low-Calorie Diet Can Extend Your Lifespan
Overeating can lead to health issues that can shorten one's life, such as obesity, diabetes and heart disease. On the other end of the spectrum, several studies have shown that restricting calorie intake below what a normal diet would dictate may lead to a longer life. In an animal study, scientists now report in ACS' Journal of Proteome Research the metabolic reasons why these … [Read more...]
Natural Metabolite can Suppress Inflammation
An international group of scientists from US, Canada, Germany and Russia has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages -- specific cells of immune system. The substance known as itaconate is released in large quantities by macrophages themselves, but until now its role remained poorly studied. Now scientists have … [Read more...]
Women with BRCA1 at High Risk of Uterine Cancer
Women who carry the BRCA1 gene mutation that dramatically increases their risk of breast and ovarian cancers are also at higher risk for a lethal form of uterine cancer, according to a study led by a Duke Cancer Institute researcher. This newly defined risk -- the first to show a conclusive link between the BRCA1 gene mutation and a small but significant chance of … [Read more...]
Inhalable Ibuprofen on the Horizon
Ibuprofen: You can buy it at any drug store, and it will help with that stabbing headache or sprained ankle. One of the ways it does so is by reducing inflammation, and it is this property that may also help patients with cystic fibrosis. Research has found that ibuprofen, when taken at high doses, helps slow the progression of lung function decline in people with … [Read more...]
Prenatal exposure to Acetaminophen may increase Autism chances
A new study has found that paracetamol (acetaminophen), which is used extensively during pregnancy, has a strong association with autism spectrum symptoms in boys and for both genders in relation to attention-related and hyperactivity symptoms. The findings were published this week in the International Journal of Epidemiology. This is the first study of its kind to … [Read more...]
Switch-Off Your Cravings
Eating a type of powdered food supplement, based on a molecule produced by bacteria in the gut, reduces cravings for high-calorie foods such as chocolate, cake and pizza, a new study suggests. Scientists from Imperial College London and the University of Glasgow asked 20 volunteers to consume a milkshake that either contained an ingredient called inulin-propionate … [Read more...]
Are we giving up on cardiac arrest patients too soon?
Physicians may be drawing conclusions too soon about survival outcomes of patients who suffered a cardiac arrest outside the hospital. A study led by Bentley Bobrow, MD, professor at the University of Arizona Colleges of Medicine in Tucson and Phoenix and co-director of the Arizona Emergency Medicine Research Center -- Phoenix, and his fellow UA emergency medicine … [Read more...]
Defense Against Free Radicals That Cause Aging
Free radicals cause cell damage and death, aging and disease, and scientists have sought new ways to repel them for years. Now, a new University of Michigan study outlines the discovery of a protein that acts as a powerful protectant against free radicals. Ironically, the protein is activated by excessive free radicals. Human mutations of the gene for this protein are … [Read more...]
Calorie-burning Pathway found in Fat Cells
Investigators at Dana-Farber Cancer Institute in collaboration with scientists at the University of California, Berkeley, have identified a natural molecular pathway that enables cells to burn off calories as heat rather than store them as fat. This raises the possibility of a new approach to treating and preventing obesity, diabetes, and other obesity-linked metabolic … [Read more...]
Air pollution linked to increased rate of kidney disease
While air pollution is known to cause respiratory and cardiovascular diseases, a new study indicates that it also likely causes damage to the kidneys. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), call for attention on the role of air pollution in the development of kidney disease in urban areas. Air … [Read more...]
The Secret of Resistant Starch
The secret ingredient is in the flour, but its impact lies within the gut. Adding resistant starch to the diets of people with metabolic syndrome can improve bacteria in the gut, according to research from South Dakota State University. These changes help lower bad cholesterol and decrease inflammation associated with obesity. The American Heart Association estimates that 34 … [Read more...]
Breaking News: Artificial Pancreas to be available by 2018
The artificial pancreas -- a device which monitors blood glucose in patients with type 1 diabetes and then automatically adjusts levels of insulin entering the body -- is likely to be available by 2018, conclude authors of a paper inDiabetologia (the journal of the European Association for the Study of Diabetes). Issues such as speed of action of the forms of insulin used, … [Read more...]
Greater Risk of Heart Failure among Overweight Youth
It comes down to starting healthy habits early. Fortunately, it's never too late to adopt a healthier lifestyle, and losing weight is great for reducing your risk of heart attack. But you can still be at a higher risk for other heart problems if you're late in changing your habits. Excessive weight at a young age puts one at a far higher risk of heart failure as … [Read more...]
Proteins Can Help Save Breast Cancer Patients
A family of proteins that help cancer cells survive and spread around the body may be associated with improved prognosis for some women receiving treatment for breast cancer, research has shown. The study, led by academics at The University of Nottingham and published online by the academic journal Oncotarget, discovered that when high levels of the protein calpain … [Read more...]
Rio Athletes may Benefit from ‘Leaky Gut’ Therapy
'Leaky gut' is a condition where the thin mucosal barrier of the gut, which plays a role in absorbing nutrients and preventing large molecules and germs from the gut entering the blood stream, becomes less effective. It is a particular problem for those taking part in heavy exercise or who are active in hot conditions. It can lead to 'heat stroke' (especially in military … [Read more...]
Butter Does Not Lead To Chronic Diseases
Butter consumption was only weakly associated with total mortality, not associated with cardiovascular disease, and slightly inversely associated (protective) with diabetes, according to a new epidemiological study which analyzed the association of butter consumption with chronic disease and all-cause mortality. This systematic review and meta-analysis, published in PLOS ONE, … [Read more...]
New Breakthrough in Brain Tumor Research
Scientists at Newcastle University, UK, have made a pioneering breakthrough in the understanding of how a fatal brain tumor grows -- which could lead to improved treatments for patients. Experts have found cells within the malignant brain tumor, glioma, rely on fats to fuel growth. This contradicts previous scientific belief that tumor cells require mainly sugars to … [Read more...]
Mannose levels may indicate diabetes risk
Even if you are not overweight, your mannose levels may indicate whether you're at risk for type 2 diabetes (T2D) or insulin resistance (IR), a Swedish study shows. Mannose, a simple sugar that occurs as a component of many natural polysaccharides, has been identified as a biomarker for diabetes, says Adil Mardinoglu, a systems biologist at KTH Royal Institute of … [Read more...]
Children drinking sports drinks have risk of obesity
A high proportion of 12-14 year olds are regularly consuming sports drinks socially, increasing their risk of obesity and tooth erosion, concludes a Cardiff University School of Dentistry survey. Published today in the British Dental Journal, the survey looked at 160 children in four schools across South Wales and concluded that children are attracted to sports drinks … [Read more...]
E-wheelchair: It Must Weigh Less
Whilst the advantages of a wheelchair with auxiliary drive are self-evident, they do not always outweigh the disadvantages. The weight of the construction can pose a physical burden on a certain group of wheelchair users, according to research from the University of Twente in The Netherlands. Mobility researcher Marieke Kloosterman investigated the effects of the … [Read more...]
Omega-3s leads to lower risk of fatal heart disease
Blood levels of seafood and plant-based omega-3 fatty acids are moderately associated with a lower risk of dying from heart attacks, according to a new epidemiological study, published in JAMA Internal Medicine, led by Liana C. Del Gobbo, Ph.D., a postdoctoral research fellow in the division of cardiovascular medicine at Stanford University School of Medicine and senior author … [Read more...]
Nanomachines to diagnose illness: Iowa State University Study
Nanomachines are the future of diagnosing and treating illness and disease. Henderson, a professor of genetics, development and cell biology at Iowa State University, along with his former graduate student Divita Mathur, studies how to build nanomachines that may have real-world medical applications someday soon. He and Mathur recently published an article in the peer-reviewed … [Read more...]
Coffee: Benefits outweigh Risks
Coffee is enjoyed by millions of people every day and the 'coffee experience' has become a staple of our modern life and culture. While the current body of research related to the effects of coffee consumption on human health has been contradictory, a study in the June issue of Comprehensive Reviews in Food Science and Food Safety, which is published by the Institute of Food … [Read more...]
New method developed to wipe out cancerous tumors
Matthew Gdovin, an associate professor in the UTSA Department of Biology, has developed a newly patented method to kill cancer cells. His discovery, described in a new study in The Journal of Clinical Oncology, may tremendously help people with inoperable or hard-to-reach tumors, as well as young children stricken with cancer. Gdovin's top-tier research involves … [Read more...]
‘Virtual Heart’ to model heart failure: A PLOS Study
A team of researchers have created a detailed computational model of the electrophysiology of congestive heart failure, a leading cause of death. This "virtual heart" could help medical researchers study new drug therapies -- according to the study published in PLOS Computational Biology. Researchers from the University of California created a model that can simulate … [Read more...]
Alcohol-use disorders (AUDs)
Adolescence is also a critical period for the development of AUDs; drinking habits can be unstable and environmental factors such as peer pressure may be substantial. This study looked at how gender and FH might affect alcohol use in a sample of 18- to 19-year-olds from the Dresden Longitudinal Study on Alcohol use in Young Adults (D-LAYA). Researchers asked 82 … [Read more...]
Get Customized New Knees
BACKGROUND: Patients with severe damage to the knee joint who suffer with progressive pain and impaired function may opt for total knee replacement. In the U.S., osteoarthritis is the most common reason for knee replacement. In a total knee replacement, the diseased knee joint is replaced with artificial parts. During the procedure, the end of the femur bone is removed and … [Read more...]
U.S.: Largest “happiness gap” among parents & non-parents
Parents in the United States generally are not as happy as those who aren't parents. Not only that, the U.S. has the largest "happiness gap" among parents compared to nonparents in 22 industrialized countries, according to a report by researchers at Baylor University, the University of Texas at Austin and Wake Forest University. The report -- prepared for the Council on … [Read more...]
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