Reversing scar tissue after a heart attack to create healthy heart muscle: this would be a game-changer in the field of cardiology and regenerative medicine. In the lab, scientists have shown it's possible to change fibroblasts (scar tissue cells) into cardiomyocytes (heart muscle cells), but sorting out the details of how this happens hasn't been easy, and using this kind of … [Read more...]
Blood test can effectively rule out breast cancer, regardless of breast density
A new study published in PLOS ONE demonstrates that Videssa Breast, a multi-protein biomarker blood test for breast cancer, is unaffected by breast density and can reliably rule out breast cancer in women with both dense and non-dense breast tissue. Nearly half of all women in the U.S. have dense breast tissue. "Women who have dense breasts are at a double disadvantage. … [Read more...]
A need for bananas? Dietary potassium regulates calcification of arteries
Bananas and avocados -- foods that are rich in potassium -- may help protect against pathogenic vascular calcification, also known as hardening of the arteries. University of Alabama at Birmingham researchers have shown, for the first time, that reduced dietary potassium promotes elevated aortic stiffness in a mouse model, as compared with normal-potassium-fed mice. Such … [Read more...]
Athletes and health aficionados: The lupine protein beverage
With its intensive colors and many blossoms, the lupine looks like an ornamental plant. Yet, the tall lupine is far too good to be used decoratively as the plant's seeds contain nutritious proteins. However, it is rather complicated to make lupines edible for humans. Researchers at the Fraunhofer Institute for Process Engineering and Packaging IVV have now developed a … [Read more...]
Understanding how gastric bypass works: Finding drug targets for obesity and diabetes
A study by a team of researchers at the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) and Shriners Hospital for Children has made a technological advancement toward accelerating the discovery of drug targets for obesity, type II diabetes and other metabolic diseases. The novel experimental and computational workflow involves the first use of rodent … [Read more...]
Low serum calcium may increase risk of sudden cardiac arrest
Sudden cardiac arrest (SCA) is fatal for over 90% of patients, and more than half of men and close to 70% of women who die of SCA have no clinical history of heart disease prior to this cardiac event. It is one of the leading causes of death in the United States and kills more people than any single cancer. Many patients who suffer SCA would not be considered high risk under … [Read more...]
New self-powered paper patch could help diabetics measure glucose during exercise
A new paper-based sensor patch developed by researchers at Binghamton University, State University of New York could allow diabetics to effectively measure glucose levels during exercise. Today's most widespread methods for glucose self-testing involve monitoring glucose levels in blood. Conventional measurements, however, are not suitable for preventing hypoglycemia … [Read more...]
Abdominal fat a key cancer driver for postmenopausal women
Body fat distribution in the trunk is more important than body weight when it comes to cancer risk in postmenopausal women, according to a study presented at the ESMO 2017 Congress in Madrid. The findings put a new spin on weight management priorities for women in this this age-group, who are prone to abdominal weight gain, said study investigator Line Mærsk Staunstrup, … [Read more...]
What mediates the beneficial effects of exercise on breast cancer outcomes?
The ability of serum obtained from women with breast cancer immediately after finishing two hours of moderate to intense exercise to prevent the growth and survival of breast cancer cells lines in vitro and in mice was attributable, at least in part, to epinephrine activation of the Hippo signaling pathway, explains new research in Cancer Research, a journal of the American … [Read more...]
Fertility research brings death of dogma, birth of hope
About 13 years ago, Northeastern professor Jonathan Tilly, a reproductive biologist, made a discovery that challenged everything scientists thought they knew about female reproduction. The long-held belief that mammals were born with a set number of eggs -- and no ability to create new ones -- was wrong. Now, Tilly and his colleagues have published a new study that "puts … [Read more...]
New Treatment for Osteoporosis Protects Patients
A new treatment for osteoporosis provides major improvements in bone density and more effective protection against fractures than the current standard treatment. These are the findings of a study published in the New England Journal of Medicine (NEJM). The study is the first that compares the effect of two osteoporosis medicines on fractures. "With the new treatment, we … [Read more...]
Eat fat, live longer?
As more people live into their 80s and 90s, researchers have delved into the issues of health and quality of life during aging. A recent mouse study at the UC Davis School of Veterinary Medicine sheds light on those questions by demonstrating that a high fat, or ketogenic, diet not only increases longevity but also improves physical strength. "The results surprised me a … [Read more...]
Nutrition has benefits for brain network organization
Nutrition has been linked to cognitive performance, but researchers have not pinpointed what underlies the connection. A new study by University of Illinois researchers found that monounsaturated fatty acids -- a class of nutrients found in olive oils, nuts and avocados -- are linked to general intelligence, and that this relationship is driven by the correlation between MUFAs … [Read more...]
Eating protein three times a day could make our seniors stronger
Loss of muscle is an inevitable consequence of aging that can lead to frailty, falls or mobility problems. Eating enough protein is one way to remedy it, but it would seem that spreading protein equally among the three daily meals could be linked to greater mass and muscle strength in the elderly. These are the findings of a study conducted at the Research Institute of the … [Read more...]
Using antidepressants during pregnancy may affect your child’s mental health
The use of antidepressants has been on the rise for many years. Between 2 and 8% of pregnant women are on antidepressants. Now researchers from the National Centre for Register-based Research at Aarhus BSS show that there is an increased risk involved in using antidepressants during pregnancy. The researchers, headed by Xiaoqin Liu, have applied register-based research … [Read more...]
Hormone replacement therapies help breast cancer grow, spread
Hormone replacement therapies, or medications containing female hormones that substitute those no longer produced by the body, often are prescribed to reduce the effects of menopausal symptoms in women. Research has indicated that women who take hormone replacement therapies have a higher incidence of breast cancer. Now, researchers at the University of Missouri have linked … [Read more...]
Gene therapy via skin could treat many diseases, even obesity
A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range of gene-based therapies to treat many human diseases. In the August 3, 2017 issue of the journal Cell Stem Cell, the researchers provide "proof-of-concept." They describe a … [Read more...]
The best place to treat type 1 diabetes might be just under your skin
A group of U of T researchers have demonstrated that the space under our skin might be an optimal location to treat type 1 diabetes (T1D). The new study, led by researchers in the University of Toronto's Institute of Biomaterials & Biomedical Engineering (IBBME), involved transplanting healthy pancreatic cells under the skin to produce insulin for blood glucose … [Read more...]
Use of cognitive abilities to care for grandkids may have driven evolution of menopause
Instead of having more children, a grandmother may pass on her genes more successfully by using her cognitive abilities to directly or indirectly aid her existing children and grandchildren. Such an advantage could have driven the evolution of menopause in humans, according to new research published in PLOS Computational Biology. Women go through menopause long before … [Read more...]
Device helps people who suffer gastroparesis, or stomach paralysis
According to the National Institutes of Health, as many as five million Americans may suffer from gastroparesis, a stomach paralysis that makes it very difficult to digest food. It affects people with diabetes and Parkinson’s disease, and for one-third of the patients, the cause is unknown. Now, a special treatment is giving people back their lives. Erica Davila has … [Read more...]
Brexit may lead to later abortions for Irish women
Pro-choice campaigners have raised concerns about the potential impact of Brexit on women travelling from Ireland to Britain for abortions. Ailbhe Smyth, spokeswoman for the Coalition to Repeal the Eighth Amendment, said she was worried about restrictions on travel or access to services that might result from the United Kingdom’s decision to leave the European … [Read more...]
Women won’t be told to give birth naturally
Midwives have dropped their campaign encouraging women to give birth naturally, according to a report. The Royal College of Midwives' campaign had run since 2005, promoting birth without medical intervention, such as an emergency caesarean. But they will no longer be told they should have babies without this intervention. Professor Cathy Warwick, chief executive of … [Read more...]
Period Taboo Endangering Women’s Health
An enduring taboo surrounding menstrual bleeding is endangering women’s health, a new study has found. A "culture of silence" around vaginal bleeding, from puberty through to menopause, is failing the needs of women and girls and means many are unable to tell the difference between what is healthy and what is not, researchers said. The study, conducted at Columbia … [Read more...]
There’s proof body shaming can be majorly detrimental to women’s health
Many, many women dread going to the doctor's office, knowing they'll be weighed and then potentially criticized for their appearance — and that's affecting their healthcare. While doctors are obviously supposed to tell their patients when they're making unhealthy decisions, which includes discussing weight gain, much of the conversation surrounding weight can be … [Read more...]
Targeted radiotherapy limits side effects of breast cancer treatment
Breast cancer patients who have radiotherapy targeted at the original tumour site experience fewer side effects five years after treatment than those who have whole breast radiotherapy, and their cancer is just as unlikely to return, according to trial results published in The Lancet. The Cancer Research UK-funded IMPORT LOW trial revealed that five years after … [Read more...]
Is There A Hidden Calcium Cholesterol Connection?
It's well known that calcium is essential for strong bones and teeth, but new research shows it also plays a key role in moderating another important aspect of health -- cholesterol. Scientists at the University of Alberta and McGill University have discovered a direct link between calcium and cholesterol, a discovery that could pave the way for new ways of treating high … [Read more...]
In assessing risk of hormone therapy for menopause, dose, not form, matters
When it comes to assessing the risk of estrogen therapy for menopause, how the therapy is delivered -- taking a pill versus wearing a patch on one's skin -- doesn't affect risk or benefit, researchers at UCLA and elsewhere have found. But with the commonly used conjugated equine estrogen, plus progestogen, the dosage does. Higher doses, especially over time, are associated with … [Read more...]
Impact of surgical modality on breast-specific sensuality
Does the type of surgery used to treat breast cancer impact a woman's sensuality and sexual function in survivorship? New research from Women & Infants Hospital analyzed the association of surgical modality with sexual function and found that breast-specific sensuality and appearance satisfaction are better with lumpectomy and may correlate with improved sexual function … [Read more...]
Assessment of bone density and fracture history can predict long-term fracture risk
Factors such as low bone density and previous fractures are commonly used to predict an individual's risk of experiencing a fracture over the next 10 years. A new analysis has found that a single bone density measurement and an assessment of fracture history in postmenopausal women can predict fracture risk over a much longer period, up to 25 years. The findings come … [Read more...]
Protein-rich diet may help soothe inflamed gut
Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat don't sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues. When the balance tilts too far toward inflammation, inflammatory bowel disease can result. Now, researchers … [Read more...]
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