The U.S. Food and Drug Administration-approved drug liraglutide has been shown to help obese patients lose weight by suppressing their appetite. However, where and how the drug acts in the brain was not fully understood, until now. A new preclinical study from the Perelman School of Medicine at the University of Pennsylvania, published in Science Translational Medicine today, … [Read more...]
New method to grow human blood vessels
A team of researchers at the University of Minnesota Medical School recently proved the ability to grow human-derived blood vessels in a pig -- a novel approach that has the potential for providing unlimited human vessels for transplant purposes. Because these vessels were made with patient-derived skin cells, they are less likely to be rejected by the recipient, helping … [Read more...]
Breastfeeding and Risks of Allergies and Asthma
Exclusive breastfeeding for 3 months was associated with a 23% lower relative risk of respiratory allergies at the age of 6 years. It was also associated with a 34% lower relative risk of asthma, but only if the children did not have a family history of asthma. Breastfeeding for 3 months, but not exclusively, was insufficient to reduce the risk of respiratory … [Read more...]
Moderate egg consumption not associated with higher cardiovascular disease risk
The relationship between egg consumption and CVD risk has been a topic of intense debate in the scientific community in recent decades. Just in the past 12 months, three published studies have reported conflicting results. The new findings update a 1999 study -- the first major analysis of eggs and cardiovascular disease -- that found no association between eggs and CVD … [Read more...]
For older adults, more physical activity could mean longer, healthier lives
Two studies demonstrate that older adults may be able to live longer, healthier lives by increasing physical activity that doesn't have to be strenuous to be effective, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2020. The EPI Scientific Sessions, March 3-6 … [Read more...]
Music Therapy helps Stroke Patients
New research has found that music therapy sessions have a positive effect on the neurorehabilitation of acute stroke patients, as well as their mood. The study -- the first large-scale investigation into the feasibility of delivering these exercises -- was led by Dr Alex Street, of Anglia Ruskin University (ARU), and was carried out on a 26-bed stroke and rehabilitation unit … [Read more...]
Individual response to COVID-19 ‘as important’ as government action
How individuals respond to government advice on preventing the spread of COVID-19 will be at least as important, if not more important, than government action, according to a new commentary from researchers at the University of Oxford and Imperial College London in the UK, and Utrecht University and the National Institute for Public Health and the Environment in the … [Read more...]
Mediterranean diet for one year promotes gut bacteria linked to ‘healthy aging’
Eating a Mediterranean diet for a year boosts the types of gut bacteria linked to 'healthy' ageing, while reducing those associated with harmful inflammation in older people, indicates a five-country study, published online in the journal Gut. As ageing is associated with deteriorating bodily functions and increasing inflammation, both of which herald the onset of … [Read more...]
Individual response to COVID-19 ‘as important’ as government action
How individuals respond to government advice on preventing the spread of COVID-19 will be at least as important, if not more important, than government action, according to a new commentary from researchers at the University of Oxford and Imperial College London in the UK, and Utrecht University and the National Institute for Public Health and the Environment in the … [Read more...]
New study associates intake of dairy milk with greater risk of breast cancer
Intake of dairy milk is associated with a greater risk of breast cancer in women, according to a new study conducted by researchers at Loma Linda University Health. Dairy, soy and risk of breast cancer: Those confounded milks, published in the International Journal of Epidemiology, found that even relatively moderate amounts of dairy milk consumption can increase women's … [Read more...]
For older adults, more physical activity could mean longer, healthier lives
Two studies demonstrate that older adults may be able to live longer, healthier lives by increasing physical activity that doesn't have to be strenuous to be effective, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2020. The EPI Scientific Sessions, March 3-6 … [Read more...]
Drinks with added sugars linked to lipid imbalance, which increases CVD risk
Drinking 12 ounces of sugary drinks more than once per day is linked to lower levels of high-density lipoprotein cholesterol (HDL-C), ("good" cholesterol), and higher levels of triglycerides, in middle aged and older adults, both of which have been shown to increase risk of cardiovascular disease. These results are from a new observational study published today in the Journal … [Read more...]
Heatwave exposure linked to increased risk of preterm birth in California
More than just causing discomfort, regional heatwaves have been associated with a number of health risks, particularly for children and the elderly. A new study by researchers at University of California San Diego identified another important at-risk group: people who are pregnant and their unborn infants. The study, published February 11, 2020 in Environment International, … [Read more...]
Antibodies: The body’s own antidepressants
If the immune system attacks its own body, it can often have devastating consequences: autoantibodies bind to the body's structures, triggering functional disorders. The receptors for glutamate, a neurotransmitter, can also become the target of autoantibodies. Researchers at the Max Planck Institute of Experimental Medicine in Göttingen have been investigating the circumstances … [Read more...]
Possible new treatment strategy for fatty liver disease
Researchers at Karolinska Institutet in Sweden have identified a molecular pathway that when silenced could restore the normal function of immune cells in people with fatty liver disease. The findings could lead to new strategies for treating the condition, which is a major health risk for people with obesity. The study is published in the scientific journal Science … [Read more...]
Researchers make asthma breakthrough
Researchers from Trinity College Dublin have made a breakthrough that may eventually lead to improved therapeutic options for people living with asthma. The researchers have uncovered a critical role for a protein (Caspase-11), which had previously never been implicated in the disease. They report their findings today [Wednesday 26th February 2020] in leading journal Nature … [Read more...]
Metals could be the link to new antibiotics
Compounds containing metals could hold the key to the next generation of antibiotics to combat the growing threat of global antibiotic resistance. University of Queensland researchers, working with a network of international collaborators, have discovered 23 previously unexplored compounds containing metals such as silver, manganese, zinc, ruthenium and iridium that have … [Read more...]
How enzymes build ‘sugar trees’
Many of the membrane proteins in eukaryotic cells are decorated with complex sugar trees called glycans. In addition to being extremely diverse, these sugar trees serve as a way to identify the respective organism, a cell type or its stage of maturity. For instance, the various blood groups in humans feature different glycans. Complex sugars that are attached to … [Read more...]
How caloric restriction prevents negative effects of aging in cells
If you want to reduce levels of inflammation throughout your body, delay the onset of age-related diseases, and live longer -- eat less food. That's the conclusion of a new study by scientists from the US and China that provides the most detailed report to date of the cellular effects of a calorie-restricted diet in rats. While the benefits of caloric restriction … [Read more...]
A Secreted Signature of Aging Cells
Senescent cells undergo an irreversible and permanent arrest of cell division and are hallmarks of both the aging process and multiple chronic diseases. Senescent cells -- and more importantly the factors they secrete, known collectively as the senescence-associated secretory phenotype (SASP) -- are widely accepted as drivers of aging and multiple age-related diseases. A new … [Read more...]
Neuron Found in Mice Could Have Implications for Effective Diet Drugs
Ever eaten something, gotten sick and then didn't want to eat that food again because of how it made you feel? That's because a signal from the gut to the brain produced that sickness, creating a taste aversion. Conventional wisdom renders there's one circuit in the brain that suppresses eating -- it comes from the stomach and makes you feel sick if you activate it too hard. … [Read more...]
Having Less Sex Linked to Earlier Menopause
Women who engage in sexual activity weekly or monthly have a lower risk of entering menopause early relative to those who report having some form of sex less than monthly, according to a new UCL study. The researchers observed that women, who reported engaging in sexual activity weekly, were 28% less likely to have experienced menopause at any given age than women who … [Read more...]
Hookah Smoke may be Associated with Increased Risk of Blood Clots
For the first time, in a study conducted in mice, researchers found that tobacco smoke from a hookah caused blood to function abnormally and be more likely to clot and quickly form blood clots, which can increase the risk of heart attack or stroke, according to new research published today in the American Heart Association's journal Arteriosclerosis, Thrombosis and Vascular … [Read more...]
America’s most widely Consumed Oil Causes Genetic changes in the Brain
New UC Riverside research shows soybean oil not only leads to obesity and diabetes, but could also affect neurological conditions like autism, Alzheimer's disease, anxiety, and depression. Used for fast food frying, added to packaged foods, and fed to livestock, soybean oil is by far the most widely produced and consumed edible oil in the U.S., according to the … [Read more...]
Real Risks Associated with Cannabis Exposure During Pregnancy
A new study from researchers at Western University and Queen's University definitively shows that regular exposure to THC, the main psychoactive ingredient in cannabis, during pregnancy has significant impact on placental and fetal development. With more than a year since the legalization of recreational cannabis in Canada, the effects of its use during pregnancy are only now … [Read more...]
Walnuts may be Good for the Gut and Help Promote Heart Health
Walnuts may not just be a tasty snack, they may also promote good-for-your-gut bacteria. New research suggests that these "good" bacteria could be contributing to the heart-health benefits of walnuts. In a randomized, controlled trial, researchers found that eating walnuts daily as part of a healthy diet was associated with increases in certain bacteria that can help promote … [Read more...]
Global Diets are Converging, with Benefits and Problems
Research carried out by the University of Kent has shown that diets are changing in complex ways worldwide. International food supply patterns are supporting healthier diets in parts of the world, but causing underweight and obesity elsewhere. They are also having important effects on environmental sustainability, with potentially worrying consequences. Dr James Bentham, … [Read more...]
Intermittent fasting: Live ‘fast,’ live longer?
For many people, the New Year is a time to adopt new habits as a renewed commitment to personal health. Newly enthusiastic fitness buffs pack into gyms and grocery stores are filled with shoppers eager to try out new diets. But, does scientific evidence support the claims made for these diets? In a review article published in the Dec. 26 issue of The New England Journal … [Read more...]
Study of cardiac muscles in flies might help you keep your heart young
Researchers may have discovered a way to turn back the clock on aging heart muscles in fruit flies, a development that could lead to new therapies for older humans with heart disease. Hua Bai, an assistant professor of genetics, development and cell biology at Iowa State University, led a study, published recently in the academic journal Autophagy, that explores the … [Read more...]
Want to turn back time? Try running a marathon
The new year means it's time to set resolutions for 2020 and new research from the Journal of the American College of Cardiology suggests running a marathon for the first time could have several health benefits. The study found that for first-time marathon runners, training and completion of the marathon was associated with reductions in blood pressure and aortic stiffening in … [Read more...]
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