Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells. Triple negative breast cancer is one of the most aggressive and fatal types of breast cancer. The research will help clinicians target breast cancer cells directly, while avoiding the adverse, toxic side effects of chemotherapy. Their study … [Read more...]
UK’s vaccine against SARS-CoV-2 is safe and induces an immune reaction, according to preliminary results
Promising early stage results from a phase 1/2 clinical trial of the UK's vaccine candidate against SARS-CoV-2 (the virus that causes COVID-19) are published today in The Lancet. The early stage trial finds that the vaccine is safe, causes few side effects, and induces strong immune responses in both parts of the immune system -- provoking a T cell response within 14 days of … [Read more...]
Urine Test Reveals Quality of Your Diet — and Whether it’s the Best Fit for Your Body
Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'. Scientists at Imperial College London in collaboration with colleagues at Northwestern University, University of Illinois, and Murdoch University, analysed levels of 46 different so-called … [Read more...]
Biomedical Researchers get Closer to Why Eczema Happens
A new study from researchers at Binghamton University, State University of New York may help to peel back the layers of unhealthy skin -- at least metaphorically speaking -- and get closer to a cure. An estimated 35 million Americans suffer from eczema, a chronic skin condition also known as atopic dermatitis. Worldwide, 2 to 5% of adults and about 15% of children suffer … [Read more...]
Studying the Role of Microbes as Mediators of Stress
Both Proteobacteria and Lactobacillus are common infant gut microbes. "We discovered, for instance, that mother's chronic prenatal psychological distress was linked to increased abundances of Proteobacteria genera in infant microbiota. In addition, chronic psychological symptoms were connected to decreased abundances of Akkermansia genera which is considered to promote … [Read more...]
Prenatal Stress Associated with Infant Gut Microbes
Mother's chronic prenatal psychological distress and elevated hair cortisol concentrations are associated with gut microbiota composition of the infant, according to a new publication from the FinnBrain research project of the University of Turku, Finland. The results help to better understand how prenatal stress can be connected to infant growth and development. The study has … [Read more...]
Loneliness Alters Your Brain’s Social Network
Social media sites aren't the only things that keep track of your social network -- your brain does, too. But loneliness alters how the brain represents relationships, according to new research published in JNeurosci. A brain region called the medial prefrontal cortex (mPFC) maintains a structured map of a person's social circles, based on closeness. People that struggle … [Read more...]
Study confirms ‘classic’ symptoms of COVID-19
A persistent cough and fever have been confirmed as the most prevalent symptoms associated with COVID-19, according to a major review of the scientific literature. Other major symptoms include fatigue, losing the ability to smell and difficulty in breathing. The study ratifies the list of symptoms listed by the World Health Organisation at the start of the … [Read more...]
Mild Thyroid Dysfunction Affects one in five women with a History of Miscarriage or Subfertility
Mild thyroid abnormalities affect up to one in five women with a history of miscarriage or subfertility which is a prolonged time span of trying to become pregnant, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. Thyroid disorders are common in women of reproductive age. Although the prevalence of thyroid … [Read more...]
Gut Bacteria may modify behavior in Worms, influencing Eating Habits
Gut bacteria are tiny but may play an out-sized role not only in the host animal's digestive health, but in their overall well-being. According to a new study in Nature, specific gut bacteria in the worm may modify the animal's behavior, directing its dining decisions. The research was funded in part by the National Institutes of Health. "We keep finding surprising roles for … [Read more...]
Fantastic muscle proteins and Where to find Them
Researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract, relax, communicate its energy needs, and adapt to exercise. Specifically, they were able to map proteins in defined subregions of the sarcomere, … [Read more...]
Renewed Hope for Treatment of Pain and Depression
Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) developed LIH383, a novel molecule that binds to and blocks a previously unknown opioid receptor in the brain, thereby modulating the levels of opioid peptides produced in the central nervous system (CNS) and potentiating their natural painkilling and antidepressant properties. … [Read more...]
Physical activity prevents almost 4 million early deaths worldwide each year
At least 3.9 million early deaths are being averted worldwide every year by people being physically active, according to a new study published in The Lancet Global Health today by researchers at the Universities of Cambridge and Edinburgh. The team behind the study argue that too often we focus on the negative health consequences of poor levels of physical activity when we … [Read more...]
Physical activity in all of its forms may help maintain muscle mass in midlife
A large study of middle-aged women shows that age-related changes in skeletal muscle are part of everyday life for women in their fifties. During this time, women transition from perimenopause to postmenopause and the production of estrogen ceases. Loss of estrogen has an effect on muscles and leads to a decline in muscle mass. Physical activity in all of its forms may help … [Read more...]
Scientists discover that nicotine promotes spread of lung cancer to the brain
Among people who have the most common type of lung cancer, up to 40% develop metastatic brain tumors, with an average survival time of less than six months. But why non-small-cell lung cancer so often spreads to the brain has been poorly understood. Now scientists at Wake Forest School of Medicine have found that nicotine, a non-carcinogenic chemical found in tobacco, … [Read more...]
Disrupted sleep increases the risk of cardiovascular disease by promoting inflammation
Sleep disruption has been shown to be associated with an increased risk of atherosclerosis, but the mechanism has been unclear. A new study in the open-access journal PLOS Biology by Raphael Vallat, Vyoma Shah, and Matthew Walker of the University of California at Berkeley and colleagues reveals that fragmented sleep exacerbates atherosclerosis and may raise the risk of stroke … [Read more...]
Repetitive negative thinking linked to dementia risk
Persistently engaging in negative thinking patterns may raise the risk of Alzheimer's disease, finds a new UCL-led study. In the study of people aged over 55, published in Alzheimer's & Dementia, researchers found 'repetitive negative thinking' (RNT) is linked to subsequent cognitive decline as well as the deposition of harmful brain proteins linked to … [Read more...]
Extra choline may help pregnant women decrease negative effects of COVID-19 on their newborns
Pregnant women who take extra choline supplements may mitigate the negative impact that viral respiratory infections, including COVID-19, can have on their babies, according to a new study from researchers in the Departments of Psychiatry and Obstetrics and Gynecology at the University of Colorado Anschutz Medical Campus. Choline is a vitamin B nutrient found in various foods … [Read more...]
Wording of vaccination messages influences behavior
When it comes to vaccination, words matter as do perceptions of what is normal behavior. An experiment by Washington State University researchers revealed that relatively small differences in messages influenced people's attitudes about the human papillomavirus or HPV vaccine, which has been shown to help prevent cancer. Young adult subjects in the study recently published … [Read more...]
High-strain exercise linked to very early pregnancy loss
In women with a history of miscarriage, higher levels of physical activity were associated with a greater risk of subclinical, or very early, pregnancy loss, according to new research at the University of Massachusetts Amherst. Among women with confirmed pregnancy, physical activity and miscarriage risk were unrelated. "Risk related to physical activity is different for … [Read more...]
Inexpensive retinal diagnostics via smartphone
Retinal damage due to diabetes is now considered the most common cause of blindness in working-age adults. In low- and middle-income countries, an eye examination via smartphone could help to detect changes at an early stage. This is shown by a new study carried out by scientists from the University of Bonn together with colleagues from Sankara Eye Hospital Bangalore (India). … [Read more...]
Obesity not related to how close you live to fast food or gyms
A new study from Lund University in Sweden has shown no correlation between obesity and how close you live to fast food restaurants or gyms. Studies from other countries have previously indicated that these factors may be important in adult obesity. The areas where we live are known to be important for our health. For example, obesity is more prevalent in deprived … [Read more...]
Adding a blend of spices to a meal may help lower inflammation
Adding an array of spices to your meal is a surefire way to make it more tasty, but new Penn State research suggests it may increase its health benefits, as well. In a randomized, controlled feeding study, the researchers found that when participants ate a meal high in fat and carbohydrates with six grams of a spice blend added, the participants had lower inflammation … [Read more...]
New approach to some mental disorders
Some of the most common mental disorders, including depression, anxiety and PTSD, might not be disorders at all, according to a recent paper by Washington State University biological anthropologists. In the paper, published in the Yearbook of Physical Anthropology, the researchers propose a new approach to mental illness that would be informed by human evolution, noting that … [Read more...]
How maternal intestinal microbiota is involved in fetal development
All mammals, including humans, are colonized by billions of microbes. These mainly live in our intestines but can also be found in the respiratory tract, on the skin and in the urogenital tract. In the gastroenterology research group of the Department for BioMedical Reserarch (DBMR) at the University of Bern and at the University Hospital Bern, Inselspital, Stephanie … [Read more...]
Dementia gene raises risk of severe COVID-19
Having a faulty gene linked to dementia doubles the risk of developing severe COVID-19, according to a large-scale study. Researchers at the University of Exeter Medical School and the University of Connecticut School of Medicine analysed data from the UK Biobank, and found high risk of severe COVID-19 infection among European ancestry participants who carry two faulty … [Read more...]
Tiny RNA that should attack coronavirus diminish with age, disease
A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report. MicroRNAs play a big role in our body in controlling gene expression, … [Read more...]
Vitamin B3 revitalizes energy metabolism in muscle disease
An international team of scientists, led by University of Helsinki reported that vitamin B3, niacin, has therapeutic effect in progressive muscle disease. Niacin delayed disease progression in patients with mitochondrial myopathy, a progressive disease with no previous curative treatments. Vitamin B3 forms have recently emerged as potent boosters of energy metabolism in … [Read more...]
A disease trigger for pancreatitis has been identified
Patients suffering from chronic pancreatitis experience an either recurring or permanent inflammation of their pancreas. "In many cases, people develop this disease because they are drinking too much alcohol or they are smoking too much. Certain medication or high levels of lipids or calcium in a patient's blood can be another cause of pancreatitis," explained Heiko Witt, one … [Read more...]
Skin-to-skin ‘kangaroo care’ shows important benefits for premature babies
A world-first study led by Monash University has demonstrated significant benefits to a premature baby's heart and brain function when held by the parent in skin-to-skin contact. Parent-infant skin-to-skin care (SSC) or kangaroo care, started in the late 1970s in Columbia when incubators to keep babies warm were not available. It is now widely recognized as a beneficial … [Read more...]
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